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Fatty acids and Glucocerebrosidase activity as potential biomarkers of stearyl-CoA desaturase inhibition; an observational study of inter- and intraday variation in healthy volunteers and patients with Parkinson's disease.

P.P.N.M Eijsvogel, A.A. Gorbenko, D. Tardiff, M. Skupien, K. Rhodes, R. Scannevin, M. de Kam, P.H.K. Kremer, E.M.J. van Brummelen, B. Robertson, G.J. Groeneveld

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Estimation of the clinical severity of Facioscapulohumeral Muscular Dystrophy (FSHD) using smartphone and remote monitoring sensor data

Ahnjili Zhuparris, Ghobad Maleki, Ingrid Koopmans, Nicole Voet, Otto Postma, Adam Cohen, Emilie van Brummelen, Robert-Jan Doll, Joris De Maeyer, Geert Jan Groeneveld

Download poster (PDF, 712.01 kb)
Behavioral biomarkers for depression drug trials: a pilot study with a novel remote digital monitoring platform

Ahnjili Zhuparris, Ghobad Maleki, Liesbeth van Londen, Ingrid Koopmans, Vincent Aalten, Iris E. Yocarini, Wessel Kraaij, Vasileios Exadaktylos, Adam Cohen, Pim Gal, Robert-Jan Doll, Geert Jan Groeneveld, Albert van Hemert, Gabriël Jacobs

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Validation of the capsaicin 1% ethanolic solution model for use in early-phase clinical drug studies

H.J. Hijma, MSc, L.M. Moss, MD, M.L. de Kam, MSc, R.J. Doll, PhD, E.M.J. van Brummelen, PharmD PhD and G.J. Groeneveld, MD PhD

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Functional central nervous system effects of the novel AMPA positive allosteric modulator (PAM) TAK-653 consistent with increased cortical excitability

Dijkstra F, Zuiker R, O’Donnell P, Klaassen E, Quanhong L, Buhl D, Ruijs T, Asgharnejad M, Murthy V, Rosen L, Jacobs G

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Clinical and Laboratory Chronic Hepatitis B Research Consortium

Consortium

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Transcranial Magnetic Stimulation as a Translational Biomarker for Modulation of AMPA Receptor Function

Patricio O’Donnell, Francis Dijkstra, Ugur Damar, Andres Pascual-Leone, Quanhong Lei, Annika de Goede, Lin Xu, Derek L. Buhl, Rob Zuiker,Titia Ruijs, Martin Lubell, Mahnaz Asgharnejad, Venkatesha Murthy, Alexander Rotenberg, Gabriel Jacobs, Laura Rosen

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Identifying healthy elderly subjects with Alzheimer Pathology more efficiently for clinical trial participation

S. Prins, A. Zhuparris, E.P. ‘t Hart, D. Ziagkos, G.J. Groeneveld

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Correlation of physical activity and pulmonary function collected via a non-invasive trial@home platform to traditional endpoints to differentiate between healthy and asthmatic children

MD Kruizinga, E Essers, N van der Heide, M Nuijsink, AJ Sprij, I Groothuis, A Zhuparris, FE Stuurman, AF Cohen, GJA Driessen

Download poster (PDF, 418.38 kb)

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