Trial Services

CHDR has more than 30 years of experience in performing early phase drug studies. We perform around 60 early phase clinical studies per year in both healthy volunteers and patients, of which 15 are first-in-human studies. Our purpose-built research unit – consisting of three floors of flexible research rooms, hotel-like long-stay accommodation and a dedicated first-in-human unit with ICU setting – is fully dedicated to executing phase I studies.

Studies are conducted by our highly knowledgeable study teams. More than 40 of our employees are medical doctors and all clinical staff are trained regularly in basic and advanced life support. In addition, the ER of the Leiden University Medical Center is located within 300 metres of our facility.

CHDR operates as a one-stop-shop, providing a full range of services:

Recruitment

With an innovative, strategic approach, CHDR’s Recruitment Department rises to the challenges of recruiting healthy volunteers and patients for a diverse range of study requirements.

Pharmacy

The GMP-licensed pharmacy of the Leiden University Medical Center (LUMC) is our full-service partner in early-stage clinical research. They prepare and deliver the pharmaceutical products, including investigational medicinal products (IMPs), and offer tailor-made solutions to help answer our sponsors’ questions.

Regulatory affairs

CHDR takes an active approach to ensuring ethical practices in research. We provides all of the services needed to optimise the development of a new protocol and streamline the approval process.

Pharmacokinetics and pharmacometrics

Over the past decade, CHDR's PK data analysts and pharmacometricians have provided in-depth pharmacokinetic (PK) and pharmacodynamic (PD) analyses to support critical decisions in the development of a range of drugs. Our team is adept at performing non-compartmental analyses and population PK/PD analyses for all types of clinical studies, at all phases of drug development. Our pharmacokinetic and pharmacometric expertise is especially extensive in the field of early clinical drug development.

Cardiology Services

The ability to identify adverse cardiac effects is a crucial part of early drug development. CHDR offers a wide range of Good Clinical Practice (GCP)-certified diagnostic procedures that can be tailored to meet the needs of the sponsor and satisfy the regulatory authorities.

Biomarker Laboratory

CHDR houses and operates a state-of-the-art cellular laboratory and can handle fresh samples collected from both healthy subjects and patients to measure a wide variety of cellular responses.

Data Management

Our data managers engage seamlessly with both internal and external operational teams from the start of a study until database lock, ensuring timely, high quality deliverables.