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Key publication (482)
Poster (19)
PhD Thesis (16)
Brochure (17)
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Annual report (6)

Impact of (chemo)radiotherapy on immune cell composition and function in cervical cancer patients.

van Meir H, Nout RA, Welters MJ, Loof NM, de Kam ML, van Ham JJ, Samuels S, Kenter GG, Cohen AF, Melief CJ, Burggraaf J, van Poelgeest MI, van der Burg SH

Oncoimmunology, 2017 May; 6(2):e1267095

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Pharmacodynamic response profiles of anxiolytic and sedative drugs.

Chen X, Broeyer F, de Kam M, Baas J, Cohen A, van Gerven J

British journal of clinical pharmacology, 2017 Apr; 83(5):1028-1038

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Pharmacokinetics and pharmacodynamics of oral mecamylamine - development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation.

Alvarez-Jimenez R, Baakman AC, Stevens J, Goulooze SC, Hart EP, Rissmann R, van Gerven JM, Groeneveld GJ

Journal of psychopharmacology (Oxford, England), 2017 Jan; 31(2):192-203

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Evidence of NI-0101 pharmacological activity, an anti-TLR4 antibody, in a randomized phase I dose escalation study in healthy volunteers receiving LPS.

Monnet E, Lapeyre G, Poelgeest EV, Jacqmin P, Graaf K, Reijers J, Moerland M, Burggraaf J, Min C

Clinical pharmacology and therapeutics, 2017 Jan; 101(2):200-208

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Effects of a single, oral 60 mg caffeine dose on attention in healthy adult subjects.

Wilhelmus MM, Hay JL, Zuiker RG, Okkerse P, Perdrieu C, Sauser J, Beaumont M, Schmitt J, van Gerven JM, Silber BY

Journal of psychopharmacology (Oxford, England), 2017 Jan; 31(2):222-232

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IMO-8400, a toll-like receptor 7, 8, and 9 antagonist, demonstrates clinical activity in a phase 2a, randomized, placebo-controlled trial in patients with moderate-to-severe plaque psoriasis.

Balak DM, van Doorn MB, Arbeit RD, Rijneveld R, Klaassen E, Sullivan T, Brevard J, Thio HB, Prens EP, Burggraaf J, Rissmann R

Clinical immunology (Orlando, Fla.), 2016 Dec

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Time related effects on functional brain connectivity after serotonergic and cholinergic neuromodulation.

Klaassens BL, Rombouts SA, Winkler AM, van Gorsel HC, van der Grond J, van Gerven JM

Human brain mapping, 2016 Dec; 38(1):308-325

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Remarkable Pharmacokinetics of Monoclonal Antibodies: A Quest for an Explanation.

Reijers JA, Moerland M, Burggraaf J

Clinical pharmacokinetics, 2016 Dec

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Quantifying Beta-Galactosylceramide Kinetics in Cerebrospinal Fluid of Healthy Subjects Using Deuterium Labeling.

Kanhai K, Goulooze SC, Stevens J, Hay JL, Dent G, Verma A, Hankemeier T, de Boer T, Meijering H, Chavez JC, Cohen AF, Groeneveld GJ

Clinical and translational science, 2016 Nov; 9(6):321-327

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