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Good Clinical Trials by removing defensive interpretation of Good Clinical Practice guidelines

Jonas M. den Heijer, Jules A. A. C. Heuberger, Hemme Hijma, Annelieke C. Kruithof, Jeroen van Smeden, Geert Jan Groeneveld, Jacobus Burggraaf, Adam Cohen

Brit Jnl Clinical Pharma. , 2021 May

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Development and Technical Validation of a Smartphone-Based Cry Detection Algorithm.

ZhuParris A, Kruizinga MD, van Gent M, Dessing E, Exadaktylos V, Doll RJ, Stuurman FE, Driessen GA, Cohen AF

Frontiers in pediatrics, 2021 May

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Stability analysis of clustering of Norris' visual analogue scale: Applying the consensus clustering approach.

Guan Z, Chen XG, Hay J, van Gerven J, Burggraaf J, de Kam M

Medicine, 2021 Apr; 100(17):e25363

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Phase 1 Clinical Trial of Losmapimod in Facioscapulohumeral Dystrophy (FSHD): Safety, Tolerability, Pharmacokinetics, and Target Engagement.

Mellion ML, Ronco L, Berends CL, Pagan L, Brooks S, van Esdonk MJ, van Brummelen EMJ, Odueyungbo A, Thompson LA, Hage M, Badrising UA, Raines S, Tracewell WG, van Engelen B, Cadavid D, Groeneveld GJ

British journal of clinical pharmacology, 2021 Apr

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Effectiveness and tolerability of personalized omalizumab treatment in patients with chronic inducible urticaria.

Buters TP, van der Velden WAC, Abdisalaam I, van Maaren MS, van Doorn MBA

The journal of allergy and clinical immunology. In practice, 2021 Apr

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Safety, pharmacokinetics and pharmacodynamics of HTL0009936, a selective muscarinic M1‐acetylcholine receptor agonist: a randomized cross‐over trial

Bakker C, Prins S, Liptrot J, Hart EP, Klaassen ES, Brown GA, Brown A, Congreve M, Weir M, Marshall FH, Stevens J, Cross DM, Tasker T, Nathan PJ, Groeneveld GJ

BJCP, 2021 Apr

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Safety, pharmacokinetics and exploratory pro-cognitive effects of HTL0018318, a selective M receptor agonist, in healthy younger adult and elderly subjects: a multiple ascending dose study.

Bakker C, Tasker T, Liptrot J, Hart EP, Klaassen ES, Doll RJ, Brown GA, Brown A, Congreve M, Weir M, Marshall FH, Cross DM, Groeneveld GJ, Nathan PJ

Alzheimer's research & therapy, 2021 Apr; 13(1):87

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Spotlight Commentary: Importance of dose redefining in the process of drug repurposing.

Radanovic I, Likic R, Groeneveld GJ

British journal of clinical pharmacology, 2021 Apr; 87(4):1705-1707

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A novel sustained-release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers.

Berends CL, Pagan L, van Esdonk MJ, Klarenbeek NB, Bergmann KR, Moerland M, van der Wel V, de Visser SJ, Büller H, de Loos F, de Vries WS, Waals H, de Leede LGJ, Burggraaf J, Kamerling IMC

Pharmacology research & perspectives, 2021 Apr; 9(2):e00739

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