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Anti-IL-17A blockade did not significantly reduce inflammatory lesions in a placebo-controlled pilot study in adult patients with moderate to severe acne.

Thiboutot DM, Craft N, Rissmann R, Gatlik E, Souquières M, Jones J, Loesche C

The Journal of dermatological treatment, 2023 Dec; 34(1):2138691

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Cognitive performance in healthy clinical trial participants and patients with the NeuroCart, a neurodegenerative disease measured with an automated neuropsychological and neurophysiological test battery.

Prins S, Borghans L, de Kam ML, Groeneveld GJ, van Gerven J

Journal of the neurological sciences, 2023 Jun

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Decreased integrity of the monoaminergic tract is associated with a positive response to MPH in patients with vascular cognitive impairment - proof of principle study STREAM-VCI.

Leijenaar JF, Ingala S, Sudre CH, Mutsaerts HM, Leeuwis AE, van der Flier WM, Scheltens P, Weinstein HC, Barkhof F, van Gerven J, Groeneveld GJ, Prins ND

Cerebral circulation - cognition and behavior, 2023 May

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Objective Home-Monitoring of Physical Activity, Cardiovascular Parameters, and Sleep in Pediatric Obesity.

Knijff JM, Houdijk ECAM, van der Kaay DCM, van Berkel Y, Filippini L, Stuurman FE, Cohen AF, Driessen GJA, Kruizinga MD

Digital biomarkers, 2023 May; 6(1):19-29

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Increased Tacrolimus Exposure in Kidney Transplant Recipients With COVID-19: Inflammation-Driven Downregulation of Metabolism as a Potential Mechanism.

Klomp SD, Meziyerh S, Vissers MFJM, Moes DJAR, Arends EJ, Teng YKO, Swen JJ, de Vries APJ

Transplant international : official journal of the European Society for Organ Transplantation, 2023 May

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Impact of oral administration of single strain spp. on immune responses to keyhole limpet hemocyanin immunization and gut microbiota: A randomized placebo-controlled trial in healthy volunteers.

Saghari M, Gal P, Grievink HW, Klaassen ES, Itano A, McHale D, Moerland M

Frontiers in immunology, 2023 May

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Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease.

van Kraaij SJW, Pereira DR, Smal B, Summo L, Konkel A, Lossie J, Busjahn A, Grammatopoulos TN, Klaassen E, Fischer R, Schunck WH, Gal P, Moerland M

Clinical and translational science, 2023 May

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First-in-patient study of OTL78 for intraoperative fluorescence imaging of prostate-specific membrane antigen-positive prostate cancer: a single-arm, phase 2a, feasibility trial.

Stibbe JA, de Barros HA, Linders DGJ, Bhairosingh SS, Bekers EM, van Leeuwen PJ, Low PS, Kularatne SA, Vahrmeijer AL, Burggraaf J, van der Poel HG

The Lancet. Oncology, 2023 May; 24(5):457-467

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A multimodal, comprehensive characterization of a cutaneous wound model in healthy volunteers.

Ten Voorde W, Saghari M, Boltjes J, de Kam ML, Zhuparris A, Feiss G, Buters TP, Prens EP, Damman J, Niemeyer-van der Kolk T, Moerland M, Burggraaf J, van Doorn MBA, Rissmann R

Experimental dermatology, 2023 Apr

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