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Integration of healthy volunteers in early phase clinical trials with immuno-oncological compounds.

Radanovic I, Klarenbeek N, Rissmann R, Groeneveld GJ, van Brummelen EMJ, Moerland M, Bosch JJ

Frontiers in oncology, 2022 Sep

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Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator.

Muehlan C, Brooks S, Vaillant C, Meinel M, Jacobs GE, Zuiker RG, Dingemanse J

Clinical pharmacology and therapeutics, 2022 Sep; 111(6):1334-1342

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Monitoring of Ex vivo Cyclosporin A Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics

Aliede E. in ’t Veld, Manon A. A. Jansen, Bertine W. Huisman, Mascha Schoonakker, Marieke L. de Kam, Dirk Jan A. R. Moes, Mariëtte I. E. van Poelgeest, Jacobus Burggraaf and Matthijss Moerland

Pharmaceutics, 2022 Sep

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Cardiovascular risk factors: The effects of ageing and smoking on the immune system, an observational clinical study

H. W. Grievink1,2, V. Smit2, B. W. Huisman1,3, P. Gal1,4, Y. Yavuz1, C. Klerks1, C. J. Binder5, I. Bot2, J. Kuiper2, A. C. Foks2 and M. Moerland1,4*

Front. Immunol., 2022 Sep

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Objective Monitoring of Facioscapulohumeral Dystrophy During Clinical Trials Using a Smartphone App and Wearables: Observational Study.

Maleki G, Zhuparris A, Koopmans I, Doll RJ, Voet N, Cohen A, van Brummelen E, Groeneveld GJ, De Maeyer J

JMIR formative research, 2022 Sep; 6(9):e31775

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Potential Role of Smartphone-Based Passive Sensing in Remote Monitoring of Patients With Cancer.

Stuijt DG, Exadaktylos V, Bins AD, Bosch JJ, van Oijen MGH

JCO clinical cancer informatics, 2022 Sep

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Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia.

Aulin LBS, Kleijburg A, Moerland M, van Hasselt JGC

Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2022 Sep; 71(9):999-1001

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Cysteine Cathepsins in Breast Cancer: Promising Targets for Fluorescence-Guided Surgery.

Linders DGJ, Bijlstra OD, Fallert LC, Hilling DE, Walker E, Straight B, March TL, Valentijn ARPM, Pool M, Burggraaf J, Basilion JP, Vahrmeijer AL, Kuppen PJK

Molecular imaging and biology, 2022 Aug

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A crossover study evaluating the sex-dependent and sensitizing effects of sleep deprivation using a nociceptive test battery in healthy subjects.

Hijma H, Koopmans I, Klaassen E, Doll RJ, Zuiker R, Groeneveld GJ

British journal of clinical pharmacology, 2022 Aug

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