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Cardiac inotropy and cardiac calcium sensitization of PanLN800(-Forte), a cationic heptamethine indocyanine fluorescent contrast agent for intraoperative pan lymph node imaging.

Faber RA, Baart VM, Bordo MW, March TL, Valentijn ARPM, Harmsen S, Pool M, Burggraaf J, Frangioni JV, Vahrmeijer AL

Toxicology and applied pharmacology, 2024 Dec

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Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascending Dose Study.

Janus A, Dumas D, Le Douce J, Marie S, Pasculli G, Bambury P, Lemarchant S, Kremer P, Godfrin Y

Neurology and therapy, 2024 Dec

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Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.

Ruijs TQ, de Cuba CMKE, Heuberger JAAC, Hutchison J, Bold J, Grønnebæk TS, Jensen KG, Chin E, Quiroz JA, Petersen TK, Flagstad P, de Kam ML, van Esdonk MJ, Klaassen E, Doll RJ, Koopmans IW, de Goede AA, Aulin LBS, Pedersen TH, Groeneveld GJ

Clinical pharmacology and therapeutics, 2024 Dec

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TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine-1-Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects.

de Cuba CMKE, de Goede AA, Klaassen ES, Otto ME, Doll RJ, Kim J, Demitrack MA, Chen R, Groeneveld GJ, Heuberger JAAC

Clinical pharmacology and therapeutics, 2024 Dec

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Remote Patient Monitoring Using Mobile Health Technology in Cancer Care and Research: Patients' Views and Preferences.

Stuijt DG, van Doeveren EEM, Kos M, Eversdijk M, Bosch JJ, Bins AD, Bak MAR, van Oijen MGH

JCO clinical cancer informatics, 2024 Nov

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Cognitive Effects of Three β-Adrenoceptor Acting Drugs in Healthy Volunteers and Patients with Parkinson's Disease.

Eijsvogel PPNM, Borghans LGJM, Prins S, Moss L, van Kraaij SJW, van Brummelen E, Klaassen E, Martin RS, Bautista E, Ford AP, Kremer PHC, Groeneveld GJ, Vargas GA

Journal of Parkinson's disease, 2024 Oct; 14(6):1149-1161

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Ex vivo fluorescence-guided resection margin assessment in breast cancer surgery using a topically applied, cathepsin-activatable imaging agent.

Linders DGJ, Bijlstra OD, Walker E, March TL, Pool M, Valentijn ARPM, Dijkhuis TH, Woltering JN, Pijl FR, Noordam G, van den Burg D, van der Sijp JRM, Guicherit OR, Marinelli AWKS, Burggraaf J, Rissmann R, Bogyo M, Hilling DE, Kuppen PJK, Straight B, Straver ME, Hazelbag HM, Basilion JP, Vahrmeijer AL

Pharmacological research, 2024 Oct

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Immunohistochemical Evaluation of Cathepsin B, L, and S Expression in Breast Cancer Patients.

Linders DGJ, Bijlstra OD, Fallert LC, Dekker-Ensink NG, March TL, Pool M, Walker E, Straight B, Basilion JP, Bogyo M, Burggraaf J, Hilling DE, Vahrmeijer AL, Kuppen PJK, Crobach ASLP

Molecular imaging and biology, 2024 Sep

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Open-Label Interventional Study in Healthy Volunteers to Evaluate NO-Mediated Vasodilation by Dermal Allyl Isothiocyanate Challenge and Whole-Body Heat Stress.

van Ruissen MCE, van Kraaij SJW, Gal P, Bakker WA, Hijma HJ, Groeneveld GJ, de Kam ML, Burggraaf J, Moerland M

Journal of experimental pharmacology, 2024 Sep

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