Central Nervous System
At CHDR, we can study the pharmacology of CNS drugs using functional test batteries such as NeuroCart, PainCart, and driving simulators, as well as imaging techniques such as resting-state fMRI and PET. Using these tools, CHDR's researchers investigate how the target systems function both in healthy subjects and in patients.
CHDR highly values the use of biomarkers to predict clinical success. We are constantly busy discovering and validating new biomarkers by combining knowledge, subject marterials and data analysis.
Immunology & Inflammation
To study the effect of compounds that target inflammatory pathways in the early phases of drug development, CHDR has developed and validated a series of in vitro, ex vivo, and in vivo tools to induce inflammation in human cells and volunteers. Additionally, we offer a comprehensive set of objective measurements and instruments to systematically quantify a compound's effects on the skin.
Cardiovascular & Metabolic disease
CHDR offers an array of reliable and accurate cardiac electrophysiology services, including comprehensive QT analyses and functional assays, and methodology to challenge the metabolic state in human subjects, allowing early evaluation of the effect of new drugs.
CHDR has broad experience with a range of imaging techniques, such as resting-state fMRI and PET. We are at the forefront of developing new imaging techniques, or improving existing techniques.
Browse our 814 publications
The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.