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Immunosuppression by hydroxychloroquine: mechanistic proof in in vitro experiments but limited systemic activity in a randomized placebo-controlled clinical pharmacology study.

In 't Veld AE, Grievink HW, van der Plas JL, Eveleens Maarse BC, van Kraaij SJW, Woutman TD, Schoonakker M, Klarenbeek NB, de Kam ML, Kamerling IMC, Jansen MAA, Moerland M

Immunologic research, 2023 Aug; 71(4):617-627

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A leucine-rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls.

Vissers MFJM, Troyer MD, Thijssen E, Pereira DR, Heuberger JAAC, Groeneveld GJ, Huntwork-Rodriguez S

Clinical and translational science, 2023 Aug; 16(8):1408-1420

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Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder.

Recourt K, de Boer P, van der Ark P, Benes H, van Gerven JMA, Ceusters M, van Nueten L, Drevets WC, Bhatacharya A, Browning M, Jacobs GE

Translational psychiatry, 2023 Jul; 13(1):266

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Oral fructose intake does not improve exercise, visual, or cognitive performance during acute normobaric hypoxia in healthy humans.

Post TE, Schmitz J, Denney C, De Gioannis R, Weis H, Pesta D, Peter A, Birkenfeld AL, Haufe S, Tegtbur U, Frings-Meuthen P, Ewald AC, Aeschbach D, Jordan J

Frontiers in nutrition, 2023 Jul

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The impact of genotype on phenoconversion by concomitant medication.

de Jong LM, Boussallami S, Sánchez-López E, Giera M, Tushuizen ME, Hoekstra M, Hawinkels LJAC, Rissmann R, Swen JJ, Manson ML

Frontiers in pharmacology, 2023 Jul

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Treatment Detection and Movement Disorder Society-Unified Parkinson's Disease Rating Scale, Part III Estimation Using Finger Tapping Tasks.

ZhuParris A, Thijssen E, Elzinga WO, Makai-Bölöni S, Kraaij W, Groeneveld GJ, Doll RJ

Movement disorders : official journal of the Movement Disorder Society, 2023 Jul

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A Phase 1B Trial in GBA1-Associated Parkinson's Disease of BIA-28-6156, a Glucocerebrosidase Activator.

den Heijer JM, Kruithof AC, Moerland M, Walker M, Dudgeon L, Justman C, Solomini I, Splitalny L, Leymarie N, Khatri K, Cullen VC, Hilt DC, Groeneveld GJ, Lansbury P

Movement disorders : official journal of the Movement Disorder Society, 2023 Jul; 38(7):1197-1208

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Current management of uveal melanoma: A review.

Bai H, Bosch JJ, Heindl LM

Clinical & experimental ophthalmology, 2023 Jul; 51(5):484-494

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Fit for purpose of on-the-road driving and simulated driving: A randomised crossover study using the effect of sleep deprivation.

Koopmans I, Doll RJ, van der Wall H, de Kam M, Groeneveld GJ, Cohen A, Zuiker R

PloS one, 2023 Jun; 18(2):e0278300

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