The ability to metabolize fructose to bypass the glucose pathway in near-anaerobic conditions appears to contribute to the extreme hypoxia tolerance of the naked-mole rats. Therefore, we hypothesized that exogenous fructose could improve endurance capacity and cognitive performance in humans exposed to hypoxia.
Oral fructose intake does not improve exercise, visual, or cognitive performance during acute normobaric hypoxia in healthy humans.
CHDR
Post TE, Schmitz J, Denney C, De Gioannis R, Weis H, Pesta D, Peter A, Birkenfeld AL, Haufe S, Tegtbur U, Frings-Meuthen P, Ewald AC, Aeschbach D, Jordan J