New publication: A Large-Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands

The most common genetic risk factor known for Parkinson's disease is a damaging variant in the GBA1 gene. However, the entire GBA1 gene has rarely been studied in a large cohort from a single population. Therefore, in collaboration with Lysosomal Therapeutics, GenomeScan and several expert centres throughout the Netherlands*, we have assessed the GBA1 gene in a total of 3402 Dutch Parkinson's disease patients using next‐generation sequencing. The study was recently published in Movement Disorders, read it here.

*Leiden University Medical Center, Erasmus Medical Center, Janssen Vaccines and Prevention, Amsterdam University Medical Centers, University Medical Center Groningen, Haga Teaching Hospital, St. Antonius Ziekenhuis, Spaarne Gasthuis, Alrijne Ziekenhuis and Meander Medical Center.