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Safety, pharmacokinetics, and pharmacodynamics of Gln‐1062, a prodrug of galantamine

Charlotte Bakker, Jasper van der Aart, Ellen P. Hart, Erica S. Klaassen, Kirsten R. Bergmann, Michiel J. van Esdonk, Denis G. Kay, Geert Jan Groeneveld

Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020 Oct

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Impact of enantiomer-specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac- a pooled analysis.

Cloesmeijer ME, van Esdonk MJ, Lynn AM, Smits A, Tibboel D, Daali Y, Olkkola KT, Allegaert K, Mian P

British journal of clinical pharmacology, 2020 Sep

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Quantification of the endogenous growth hormone and prolactin lowering effects of a somatostatin-dopamine chimera using population PK/PD modeling.

van Esdonk MJ, Burggraaf J, Dehez M, van der Graaf PH, Stevens J

Journal of pharmacokinetics and pharmacodynamics, 2020 Apr

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Model informed quantification of the feed-forward stimulation of growth hormone by growth hormone-releasing hormone.

van Esdonk MJ, Burggraaf J, van der Graaf PH, Stevens J

British journal of clinical pharmacology, 2020 Mar

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Pharmacokinetics of intravenous and inhaled salbutamol and tobramycin: an exploratory study to investigate the potential of exhaled breath condensate as a matrix for pharmacokinetic analysis.

Kruizinga MD, Birkhoff WAJ, van Esdonk MJ, Klarenbeek NB, Cholewinski T, Nelemans T, Dröge MJ, Cohen AF, Zuiker RGJA

British journal of clinical pharmacology, 2019 Nov

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Clinical trial simulations of the interaction between cannabidiol and clobazam and effect on drop-seizure frequency.

Bergmann KR, Broekhuizen K, Groeneveld GJ

British journal of clinical pharmacology, 2019 Oct

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The Oral Pheneticillin Absorption Test: An Accurate Method to Identify Patients with Inadequate Oral Pheneticillin Absorption

Anneke C. Dijkmans, Dinemarie M. Kweekel, Jaap T. van Dissel, Michiel J. van Esdonk , Ingrid M. C. Kamerling and Jacobus Burggraaf

Antibiotics , 2019 Sep

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The simplified oral flucloxacillin absorption test: an accurate method to identify patients with inadequate oral flucloxacillin absorption.

Dijkmans AC, Kweekel DM, Balmforth C, van Esdonk MJ, van Dissel JT, Burggraaf J, Kamerling IMC

The Netherlands journal of medicine, 2019 Sep; 77(7):255-260

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A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery.

de Valk KS, Handgraaf HJ, Deken MM, Sibinga Mulder BG, Valentijn AR, Terwisscha van Scheltinga AG, Kuil J, van Esdonk MJ, Vuijk J, Bevers RF, Peeters KC, Holman FA, Frangioni JV, Burggraaf J, Vahrmeijer AL

Nature communications, 2019 Jul; 10(1):3118

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