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Proof of pharmacology of Org 48775-0, a p38 MAP kinase inhibitor, in healthy volunteers.

Moerland M, Kales AJ, Broekhuizen K, Nässander U, Nelissen R, de Kam ML, Peeters PAM, Burggraaf J

British journal of clinical pharmacology, 2020 Nov

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Safety, pharmacokinetics, and pharmacodynamics of Gln‐1062, a prodrug of galantamine

Charlotte Bakker, Jasper van der Aart, Ellen P. Hart, Erica S. Klaassen, Kirsten R. Bergmann, Michiel J. van Esdonk, Denis G. Kay, Geert Jan Groeneveld

Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020 Oct

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Impact of enantiomer-specific changes in pharmacokinetics between infants and adults on the target concentration of racemic ketorolac- a pooled analysis.

Cloesmeijer ME, van Esdonk MJ, Lynn AM, Smits A, Tibboel D, Daali Y, Olkkola KT, Allegaert K, Mian P

British journal of clinical pharmacology, 2020 Sep

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Quantification of the endogenous growth hormone and prolactin lowering effects of a somatostatin-dopamine chimera using population PK/PD modeling.

van Esdonk MJ, Burggraaf J, Dehez M, van der Graaf PH, Stevens J

Journal of pharmacokinetics and pharmacodynamics, 2020 Apr

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Model informed quantification of the feed-forward stimulation of growth hormone by growth hormone-releasing hormone.

van Esdonk MJ, Burggraaf J, van der Graaf PH, Stevens J

British journal of clinical pharmacology, 2020 Mar

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Pharmacokinetics of intravenous and inhaled salbutamol and tobramycin: an exploratory study to investigate the potential of exhaled breath condensate as a matrix for pharmacokinetic analysis.

Kruizinga MD, Birkhoff WAJ, van Esdonk MJ, Klarenbeek NB, Cholewinski T, Nelemans T, Dröge MJ, Cohen AF, Zuiker RGJA

British journal of clinical pharmacology, 2019 Nov

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Clinical trial simulations of the interaction between cannabidiol and clobazam and effect on drop-seizure frequency.

Bergmann KR, Broekhuizen K, Groeneveld GJ

British journal of clinical pharmacology, 2019 Oct

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Fluctuations in Pharmacokinetics Profiles of Monoclonal Antibodies.

Grabowski T, Reijers JAA, Burmańczuk A, Chełmońska-Soyta A

European journal of drug metabolism and pharmacokinetics, 2019 Oct; 44(5):585-589

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The Oral Pheneticillin Absorption Test: An Accurate Method to Identify Patients with Inadequate Oral Pheneticillin Absorption

Anneke C. Dijkmans, Dinemarie M. Kweekel, Jaap T. van Dissel, Michiel J. van Esdonk , Ingrid M. C. Kamerling and Jacobus Burggraaf

Antibiotics , 2019 Sep

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