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Anti-IL-17A blockade did not significantly reduce inflammatory lesions in a placebo-controlled pilot study in adult patients with moderate to severe acne.

Thiboutot DM, Craft N, Rissmann R, Gatlik E, Souquières M, Jones J, Loesche C

The Journal of dermatological treatment, 2023 Dec; 34(1):2138691

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Preclinical evaluation of EpCAM-binding designed ankyrin repeat proteins (DARPins) as targeting moieties for bimodal near-infrared fluorescence and photoacoustic imaging of cancer.

Houvast RD, Badr N, March T, de Muynck LDAN, Sier VQ, Schomann T, Bhairosingh S, Baart VM, Peeters JAHM, van Westen GJP, Plückthun A, Burggraaf J, Kuppen PJK, Vahrmeijer AL, Sier CFM

European journal of nuclear medicine and molecular imaging, 2023 Aug

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Item response theory in early phase clinical trials: Utilization of a reference model to analyze the Montgomery-Åsberg Depression Rating Scale.

Otto ME, Bergmann KR, de Kam ML, Recourt K, Jacobs GE, van Esdonk MJ

CPT: pharmacometrics & systems pharmacology, 2023 Aug

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Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder.

Recourt K, de Boer P, van der Ark P, Benes H, van Gerven JMA, Ceusters M, van Nueten L, Drevets WC, Bhatacharya A, Browning M, Jacobs GE

Translational psychiatry, 2023 Jul; 13(1):266

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The impact of genotype on phenoconversion by concomitant medication.

de Jong LM, Boussallami S, Sánchez-López E, Giera M, Tushuizen ME, Hoekstra M, Hawinkels LJAC, Rissmann R, Swen JJ, Manson ML

Frontiers in pharmacology, 2023 Jul

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Treatment Detection and Movement Disorder Society-Unified Parkinson's Disease Rating Scale, Part III Estimation Using Finger Tapping Tasks.

ZhuParris A, Thijssen E, Elzinga WO, Makai-Bölöni S, Kraaij W, Groeneveld GJ, Doll RJ

Movement disorders : official journal of the Movement Disorder Society, 2023 Jul

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Fit for purpose of on-the-road driving and simulated driving: A randomised crossover study using the effect of sleep deprivation.

Koopmans I, Doll RJ, van der Wall H, de Kam M, Groeneveld GJ, Cohen A, Zuiker R

PloS one, 2023 Jun; 18(2):e0278300

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Cognitive performance in healthy clinical trial participants and patients with the NeuroCart, a neurodegenerative disease measured with an automated neuropsychological and neurophysiological test battery.

Prins S, Borghans L, de Kam ML, Groeneveld GJ, van Gerven J

Journal of the neurological sciences, 2023 Jun

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Characterization of the Pharmacokinetic and Pharmacodynamic Profile of Apraglutide, a Glucagon-Like Peptide-2 Analog, in Healthy Volunteers

Bolognani F, Kruithof AC, Schulthess P, Machacek M, de Kam ML, Bergmann KR, van Gent M, Moerland M, Crenn P, Greig G, Gal P

The Journal of pharmacology and experimental therapeutics, 2023 Jun

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