Key publication
923
Therapeutic Areas
Methods & challenges

Key publication

Influence of heparin and a low molecular weight heparinoid on specific endogenous and exogenous fibrinolytic factors during rest and exercise.

Key publication

Highly variable anticoagulant response after subcutaneous administration of high-dose (12,500 IU) heparin in patients with myocardial infarction and healthy volunteers.

Key publication

Effects of temazepam on saccadic eye movements: concentration-effect relationships in individual volunteers.

Key publication

Pronounced effects of the combination of a new thromboxane antagonist (GR32191) and heparin on bleeding time in man.

Key publication

Diurnal rhythm in anticoagulant effect of heparin during a low dose constant rate infusion. A study in healthy volunteers.

Key publication

Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers.

Key publication

Effect of morphological abnormalities on blood retinal barrier permeability in diabetic retinopathy.

Key publication

Long-term effects of tolrestat on symptomatic diabetic sensory polyneuropathy.

Key publication

A multicentre trial of the aldose-reductase inhibitor tolrestat, in patients with symptomatic diabetic peripheral neuropathy. North European Tolrestat Study Group.