Key publication
906
Therapeutic Areas
Methods & challenges

Key publication

Cimetidine does not influence the metabolism of the H1-receptor antagonist ebastine to its active metabolite carebastine.

Key publication

Good clinical practice: a question of balance.

Key publication

Pharmacodynamic interactions of diazepam and intravenous alcohol at pseudo steady state.

Key publication

The pharmacokinetic and pharmacodynamic interactions of ramipril with propranolol.

Key publication

Carbamazepine and lamotrigine in healthy volunteers: relevance to early tolerance and clinical trial dosage.

Key publication

Comparative effects of felodipine, nitrendipine and nifedipine in healthy subjects: concentration-effect relationships of racemic drugs and enantiomers.

Key publication

Stereoselective pharmacokinetics of oral felodipine and nitrendipine in healthy subjects: correlation with nifedipine pharmacokinetics.

Key publication

CNS-related performance and haemodynamics of metoprolol-Oros and propranolol after single and 3 days dosing in healthy volunteers.

Key publication

The bioavailability of digoxin from three oral formulations measured by a specific h.p.l.c. assay.