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Reversal of opioid-induced respiratory depression by BK-channel blocker GAL021: A pharmacokinetic-pharmacodynamic modeling study in healthy volunteers.

Roozekrans M, Olofsen E, van der Schrier R, van Gerven J, Peng S, McLeod J, Dahan A

Clinical pharmacology and therapeutics, 2015 May; 97(6):641-9

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Kinetics of TH2 biomarkers in sputum of asthmatics following inhaled allergen.

Zuiker RG, Ruddy MK, Morelli N, Mogg R, Rivas VM, van Dyck K, De Lepeleire I, Tanen MR, Boot JD, Kamerling IM, Diamant Z

European clinical respiratory journal, 2015 May

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The use of biomarkers in human pharmacology (Phase I) studies.

Cohen AF, Burggraaf J, van Gerven JM, Moerland M, Groeneveld GJ

Annual review of pharmacology and toxicology, 2015 Apr

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Lessons Learned and Potentials for Improvement in CNS Drug Development: ISCTM Section on Designing the Right Series of Experiments.

Szabo ST, Kinon BJ, Brannan SK, Krystal AK, van Gerven JM, Mahableshwarkar A, Sachs GS

Innovations in clinical neuroscience, 2015 Apr; 12(3-4):11S-25S

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Translational and Early Phase Strategies for Treatment Development: Report of ISCTM Autumn 2013 Symposium.

Young JW, Potter WZ, Riley S, Groeneveld GJ, Kinon BJ, Egan MF, Feltner DE

Innovations in clinical neuroscience, 2015 Apr; 12(3-4):5S-10S

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Optimizing the glutamatergic challenge model for psychosis, using S+ -ketamine to induce psychomimetic symptoms in healthy volunteers.

Kleinloog D, Uit den Boogaard A, Dahan A, Mooren R, Klaassen E, Stevens J, Freijer J, van Gerven J

Journal of psychopharmacology (Oxford, England), 2015 Mar; 29(4):401-13

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The return of the prodigal son and the extraordinary development route of antibody TGN1412 - lessons for drug development and clinical pharmacology.

Kenter MJ, Cohen AF

British journal of clinical pharmacology, 2015 Mar; 79(4):545-7

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The effects of the nonselective benzodiazepine lorazepam and the α2 /α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels.

Te Beek ET, Chen X, Jacobs GE, Nahon KJ, de Kam ML, Lappalainen J, Cross AJ, van Gerven JM, Hay JL

Clinical pharmacology in drug development, 2015 Feb; 4(2):149-54

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First proof of pharmacology in humans of a novel glucagon receptor antisense drug.

van Dongen MG, Geerts BF, Morgan ES, Brandt TA, de Kam ML, Romijn JA, Cohen AF, Bhanot S, Burggraaf J

Journal of clinical pharmacology, 2015 Feb; 55(3):298-306

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