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Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery.

Hay JL, Okkerse P, van Amerongen G, Groeneveld GJ

Journal of visualized experiments : JoVE, 2016 Apr

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Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses.

Welters MJ, van der Sluis TC, van Meir H, Loof NM, van Ham VJ, van Duikeren S, Santegoets SJ, Arens R, de Kam ML, Cohen AF, van Poelgeest MI, Kenter GG, Kroep JR, Burggraaf J, Melief CJ, van der Burg SH

Science translational medicine, 2016 Apr; 8(334):334ra52

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Implications of the BIA-102474-101 study for review of first-into-human clinical trials.

Eddleston M, Cohen AF, Webb DJ

British journal of clinical pharmacology, 2016 Mar; 81(4):582-6

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Pharmacokinetic/pharmaco-dynamic modelling and simulation of the effects of different cannabinoid receptor type 1 antagonists on Δ(9)-tetrahydrocannabinol challenge tests.

Guan Z, Klumpers LE, Oyetayo OO, Heuberger J, van Gerven JM, Stevens J

British journal of clinical pharmacology, 2016 Mar; 81(4):713-23

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A PK-PD model-based assessment of sugammadex effects on coagulation parameters.

Bosch R, van Lierop MJ, de Kam PJ, Kruithof AC, Burggraaf J, de Greef R, Visser SA, Johnson-Levonas AO, Kleijn HJ

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016 Mar

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Recombinant human pentraxin-2 therapy in patients with idiopathic pulmonary fibrosis: safety, pharmacokinetics and exploratory efficacy.

van den Blink B, Dillingh MR, Ginns LC, Morrison LD, Moerland M, Wijsenbeek M, Trehu EG, Bartholmai BJ, Burggraaf J

The European respiratory journal, 2016 Feb; 47(3):889-97

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NS11821, a partial subtype-selective GABAA agonist, elicits selective effects on the central nervous system in randomized controlled trial with healthy subjects.

Zuiker RG, Chen X, Østerberg O, Mirza NR, Muglia P, de Kam M, Klaassen ES, van Gerven JM

Journal of psychopharmacology (Oxford, England), 2016 Feb; 30(3):253-62

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Identifying 24 h variation in the pharmacokinetics of levofloxacin: a population pharmacokinetic approach.

Kervezee L, Stevens J, Birkhoff W, Kamerling IM, de Boer T, Dröge M, Meijer JH, Burggraaf J

British journal of clinical pharmacology, 2016 Jan; 81(2):256-68

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First in human study with a prodrug of galantamine: Improved benefit-risk ratio?

Baakman AC, 't Hart E, Kay DG, Stevens J, Klaassen ES, Maelicke A, Groeneveld GJ

Alzheimer's & dementia (New York, N. Y.), 2016 Jan; 2(1):13-22

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