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False negatives in GBA1 sequencing due to polymerase dependent allelic imbalance.

den Heijer JM, Schmitz A, Lansbury P, Cullen VC, Hilt DC, Bonifati V, Groeneveld GJ

Scientific reports, 2021 Jan; 11(1):161

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Towards remote monitoring in pediatric care and clinical trials-Tolerability, repeatability and reference values of candidate digital endpoints derived from physical activity, heart rate and sleep in healthy children.

Kruizinga MD, Heide NV, Moll A, Zhuparris A, Yavuz Y, Kam ML, Stuurman FE, Cohen AF, Driessen GJA

PloS one, 2021 Jan

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Comprehensive evaluation of microneedle-based intradermal adalimumab delivery versus subcutaneous administration: results of a randomized controlled trial.

Jacobse J, Ten Voorde W, Tandon A, Romeijn SG, Grievink HW, van der Maaden K, van Esdonk MJ, Moes DJAR, Loeff F, Bloem K, de Vries A, Rispens T, Wolbink G, de Kam M, Ziagkos D, Moerland M, Jiskoot W, Bouwstra J, Burggraaf J, Schrier L, Rissmann R, Ten Cate R

British journal of clinical pharmacology, 2021 Jan

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Experience in Genetic Counseling for Variants in Parkinson's Disease.

den Heijer JM, van Hilten JJ, Kievit AJA, Bonifati V, Groeneveld GJ

Movement disorders clinical practice, 2021 Jan; 8(1):33-36

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First-in-man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M -receptor partial agonist for the treatment of dementias.

Bakker C, Tasker T, Liptrot J, Hart EP, Klaassen ES, Prins S, van der Doef TF, Brown GA, Brown A, Congreve M, Weir M, Marshall FH, Cross DM, Groeneveld GJ, Nathan PJ

British journal of clinical pharmacology, 2020 Dec

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Assessment of risks associated with SARS-CoV-2 experimental human infection studies.

Kuiper VP, Rosendaal FR, Kamerling IMC, Visser LG, Roestenberg M

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Nov

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Proof of pharmacology of Org 48775-0, a p38 MAP kinase inhibitor, in healthy volunteers.

Moerland M, Kales AJ, Broekhuizen K, Nässander U, Nelissen R, de Kam ML, Peeters PAM, Burggraaf J

British journal of clinical pharmacology, 2020 Nov

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Safety, pharmacokinetics and pharmacodynamics of SBT-020 in patients with early stage Huntington's disease, a 2-part study.

van Diemen MPJ, Hart EP, Abbruscato A, Mead L, van Beelen I, Bergheanu SC, Hameeteman PW, Coppen E, Winder JY, Moerland M, Kan H, van der Grond J, Webb A, Roos RAC, Groeneveld GJ

British journal of clinical pharmacology, 2020 Nov

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The association between body temperature and electrocardiographic parameters in normothermic healthy volunteers.

Fienieg B, Hassing GJ, van der Wall HEC, van Westen GJP, Kemme MJB, Adiyaman A, Elvan A, Burggraaf J, Gal P

Pacing and clinical electrophysiology : PACE, 2020 Nov

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