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The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • Effects of Brexanolone on Resting-state and Transcranial Magnetic Stimulation Evoked Electroencephalography A randomized, double-blind, double-dummy, 4-period crossover, placebo and active comparator-controlled study

    Catherine M.K.E. de Cuba, Luke S. Watson, Naser Hakimi, Annika A. de Goede, Gabriel E. Jacobs, Aaron Koralek, Anne C. Smith, Jason Johannesen, Kemi Bankole, Jeff Wald, Patricio O’Donnell, Derek L. Buhl, Jules A.A.C. Heuberger

    Download poster (PDF, 815.09 kb)

  • Novel LINE-1 Reverse Transcriptase Inhibitors Can Suppress Type I Interferon Responses and Are Promising Therapeutics for Lupus

    Wenyan Miao, Digna de Bruin, Cedric Arisdakessian, Jannik Rousel, Jared Steranka, Matthijs Moerland, Eric Jacobson, Mehrnaz Gharaee-Kermani, Liyang Diao, Craig Dobry, Nafeeza Hafeez, Brian Desrosiers, Michelle Kahlenberg, Heike Keilhack, Robert Rissmann, Keith Wilcoxen, and Tessa Niemeyer-van der Kolk

    Download poster (PDF, 1.03 mb)

  • Multimodal assessments of the treatment response of guselkumab in mild psoriasis patients: an exploratory randomized placebo-controlled clinical trial

    Menthe E. Bergmans, Jannik Rousel, Tessa Niemeyer-van der Kolk, Roman Bohoslavsky, Naomi B. Klarenbeek, Robert Rissmann, Martijn B.A. van Doorn, and the Next-Generation ImmunoDermatology Consortium

    Download poster (PDF, 743.25 kb)

  • Validation of the Virtual Reality-PainCart: a randomized, placebo-controlled, two-way crossover study with diazepam

    K.P.W. Rietdijk, I.W. Koopmans, R. Bohoslavsky, R.J. Doll, G.J. Groeneveld

    Download poster (PDF, 554.13 kb)

  • De-risking clinical trials: forecasting and preventing disasters by pursuing an IB-derisk approach

    J van Smeden, FM Dijkstra, AF Cohen, JMA van Gerven, J Burggraaf

    Download poster (PDF, 937.46 kb)

  • Inter- and intra-day variability in β-glucocerebrosidase activity and pathway biomarkers in healthy volunteers and patients with Parkinson’s disease with a GBA1 mutation

    Jurrian P. van der Valk, Daniël B. Dumas, Eva Thijssen , Diana R. Pereira, Wieke Grievink, Yalçin Yavuz, Cedric Pesch, Daniel Ysselstein, Mackenzie Hagey, Omer Siddiqui, Jesse M. Cedarbaum, Kevin W. Hunt, Philip H.C. Kremer

    Download poster (PDF, 621.09 kb)

  • Effects of levetiracetam in patients with generalized epilepsy on Transcranial Magnetic Stimulation

    CatherineM.E. de Cuba, Marjet L. Claessens, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Michel J.A.M. van Putten, Geert Jan Groeneveld, Jules A.A.C. Heuberger

    Download poster (PDF, 338.45 kb)

  • Effects of the selective sphingosine-1-phosphate subtype 1 receptor modulator, TRV045, on cortical excitability using resting-state EEG and transcranial magnetic stimulation 

    Catherine M.K.E. de Cuba1,2, Annika A. de Goede1, Erica Klaassen1, Robert J. Doll1, Geert Jan Groeneveld1,2, Jessica Kim3, Mark A. Demitrack3, Jules A.A.C. Heuberger1 

    Download poster (PDF, 367.84 kb)

  • Guselkumab induction therapy has long-lasting efficacy in mild psoriasis patients

    Robert Rissmann, PhD, Jannik Rousel, M.E. Bergmans, MD, L.W.J. van der Meulen, MD, L. Pagan, MD, D.T. de Bruin, MD, M.L. de Kam, N.B. Klarenbeek, MD, PhD, J.A. Bouwstra, PhD, M.M.B. Seyger, MD, PhD, J.M.P.A. van den Reek, MD, PhD, T. Niemeyer-van der Kolk, MD, PhD, M.B.A. van Doorn, MD, PhD, the Next Generation ImmunoDermatolgy (NGID) consortium

    Download poster (PDF, 609.12 kb)

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    Participate in a Clinical Trial proefpersoon.nl

Browse 1148 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Engineering and Analytics
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1148 publications in the CHDR library

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