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The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • Safety, pharmacokinetics, and pharmacodynamics of Gln‐1062, a prodrug of galantamine

    Charlotte Bakker, Jasper van der Aart, Ellen P. Hart, Erica S. Klaassen, Kirsten R. Bergmann, Michiel J. van Esdonk, Denis G. Kay, Geert Jan Groeneveld

    Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020 Oct

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  • A Large-Scale Full GBA1 Gene Screening in Parkinson's Disease in the Netherlands.

    den Heijer JM, Cullen VC, Quadri M, Schmitz A, Hilt DC, Lansbury P, Berendse HW, van de Berg WDJ, de Bie RMA, Boertien JM, Boon AJW, Contarino MF, van Hilten JJ, Hoff JI, van Mierlo T, Munts AG, van der Plas AA, Ponsen MM, Baas F, Majoor-Krakauer D, Bonifati V, Laar T, Groeneveld GJ

    Movement disorders : official journal of the Movement Disorder Society, 2020 Jul

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  • Utility of Animal Models to Understand Human Alzheimer's Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals.

    Qin T, Prins S, Groeneveld GJ, Van Westen G, de Vries HE, Wong YC, Bischoff LJM, de Lange ECM

    International journal of molecular sciences, 2020 Apr

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  • Quantification of tremor using consumer product accelerometry is feasible in patients with essential tremor and Parkinson's disease: a comparative study.

    van Brummelen EMJ, Ziagkos D, de Boon WMI, Hart EP, Doll RJ, Huttunen T, Kolehmainen P, Groeneveld GJ

    Journal of clinical movement disorders, 2020 Apr

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  • Simultaneous tracking of psychophysical detection thresholds and evoked potentials to study nociceptive processing.

    van den Berg B, Doll RJ, Mentink ALH, Siebenga PS, Groeneveld GJ, Buitenweg JR

    Behavior research methods, 2020 Jan

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  • Pain-related changes in cutaneous innervation of patients suffering from bortezomib-induced, diabetic or chronic idiopathic axonal polyneuropathy.

    Bechakra M, Nieuwenhoff MD, Rosmalen JV, Jan Groeneveld G, J P M Huygen F, Zeeuw CI, Doorn PAV, Jongen JLM

    Brain research, 2020 Jan

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  • Methylphenidate and galantamine in patients with vascular cognitive impairment-the proof-of-principle study STREAM-VCI.

    Leijenaar JF, Groeneveld GJ, Klaassen ES, Leeuwis AE, Scheltens P, Weinstein HC, van Gerven JMA, Barkhof F, van der Flier WM, Prins ND

    Alzheimer's research & therapy, 2020 Jan; 12(1):10

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  • Usefulness of Plasma Amyloid as a Prescreener for the Earliest Alzheimer Pathological Changes Depends on the Study Population.

    Prins S, Zhuparris A, Groeneveld GJ

    Annals of neurology, 2019 Nov

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  • Pharmacogenetic interactions in amyotrophic lateral sclerosis: a step closer to a cure?

    van Eijk RPA, Eijkemans MJC, Nikolakopoulos S, Jansen MD, Westeneng HJ, van Eijk KR, van der Spek RAA, van Vugt JJFA, Piepers S, Groeneveld GJ, Veldink JH, van den Berg LH, van Es MA

    The pharmacogenomics journal, 2019 Oct

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Browse 1079 publications in the CHDR library

  • Clinical studies & Development
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  • People
  • Education
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Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Engineering and Analytics
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1079 publications in the CHDR library

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