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Differences in corneal nerve fiber density and fiber length in patients with painful chronic idiopathic axonal polyneuropathy and diabetic polyneuropathy.

26 July 2024. doid: 10.1002/mus.28213

Nieuwenhoff MD, Nguyen HT, Niehof SP, Huygen FJPM, Verma A, Klaassen ES, Bechakra M, Geelhoed WJ, Jongen JLM, Moll AC, Vrancken AFJE, Petzold A, Groeneveld GJ

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Corneal confocal microscopy (CCM) detects small nerve fiber loss and correlates with skin biopsy findings in diabetic neuropathy. In chronic idiopathic axonal polyneuropathy (CIAP) this correlation is unknown. Therefore, we compared CCM and skin biopsy in patients with CIAP to healthy controls, patients with painful diabetic neuropathy (PDN) and diabetics without overt neuropathy (DM).

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