Key publication
893
Therapeutic Areas
Methods & challenges

Key publication

Effects of increased liver blood flow on the kinetics and dynamics of recombinant tissue-type plasminogen activator.

Key publication

Pharmacokinetic and pharmacodynamic profiles of sumatriptan in migraine patients with headache recurrence or no response.

Key publication

Self-medication of a single headache episode with ketoprofen, ibuprofen or placebo, home-monitored with an electronic patient diary.

Key publication

Estimating impossible curves using NONMEM.

Key publication

Pharmacokinetics of the conventional and microemulsion formulations of cyclosporine in pancreas-kidney transplant recipients with gastroparesis.

Key publication

Specific stimulation of brain serotonin mediated neurotransmission by dexfenfluramine does not restore growth hormone responsiveness in obese women.

Key publication

Tolrestat pharmacokinetic and pharmacodynamic effects on red blood cell sorbitol levels in normal volunteers and in patients with insulin-dependent diabetes.

Key publication

Plasma amino acid ratios related to brain serotonin synthesis in response to food intake in bulimia nervosa.

Key publication

Effect of grapefruit juice on blood cyclosporin concentration.