Key publication
909
Therapeutic Areas
Methods & challenges

Key publication

Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers.

Key publication

Effect of morphological abnormalities on blood retinal barrier permeability in diabetic retinopathy.

Key publication

Long-term effects of tolrestat on symptomatic diabetic sensory polyneuropathy.

Key publication

A multicentre trial of the aldose-reductase inhibitor tolrestat, in patients with symptomatic diabetic peripheral neuropathy. North European Tolrestat Study Group.

Key publication

Intraindividual variability in nifedipine pharmacokinetics and effects in healthy subjects.

Key publication

Serious intercurrent disease in healthy volunteers in clinical pharmacological research.

Key publication

Liver blood flow as a major determinant of the clearance of recombinant human tissue-type plasminogen activator.

Key publication

Self-selection for personality variables among healthy volunteers.

Key publication

Assessment of hepatic blood flow in healthy subjects by continuous infusion of indocyanine green.