Key publication
906
Therapeutic Areas
Methods & challenges

Key publication

A multicentre trial of the aldose-reductase inhibitor tolrestat, in patients with symptomatic diabetic peripheral neuropathy. North European Tolrestat Study Group.

Key publication

Intraindividual variability in nifedipine pharmacokinetics and effects in healthy subjects.

Key publication

Serious intercurrent disease in healthy volunteers in clinical pharmacological research.

Key publication

Liver blood flow as a major determinant of the clearance of recombinant human tissue-type plasminogen activator.

Key publication

Self-selection for personality variables among healthy volunteers.

Key publication

Assessment of hepatic blood flow in healthy subjects by continuous infusion of indocyanine green.

Key publication

Studies of interaction of a low-molecular-weight heparinoid (Org 10172) with cloxacillin and ticarcillin in healthy male volunteers.

Key publication

Influence of gastric acidity on the bioavailability of digoxin.

Key publication

The pharmacokinetics of recombinant double-chain t-PA (duteplase): effects of bolus injection, infusions, and administration by weight in patients with myocardial infarction.