Key publication
928
Therapeutic Areas
Methods & challenges

Key publication

Pharmacokinetics of saruplase, a recombinant unglycosylated human single-chain urokinase-type plasminogen activator and its effects on fibrinolytic and haemostatic parameters in healthy male subjects.

Key publication

A comparison of the concentration-effect relationships of midazolam for EEG-derived parameters and saccadic peak velocity.

Key publication

Interaction study between nifedipine and recombinant tissue-type plasminogen activator in healthy subjects.

Key publication

A cross-over comparison of the anti-clotting effects of three low molecular weight heparins and glycosaminoglycuronan.

Key publication

Cimetidine does not influence the metabolism of the H1-receptor antagonist ebastine to its active metabolite carebastine.

Key publication

Good clinical practice: a question of balance.

Key publication

Pharmacodynamic interactions of diazepam and intravenous alcohol at pseudo steady state.

Key publication

The pharmacokinetic and pharmacodynamic interactions of ramipril with propranolol.

Key publication

Carbamazepine and lamotrigine in healthy volunteers: relevance to early tolerance and clinical trial dosage.