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A randomized Phase 2 study to evaluate the orexin-2 receptor antagonist seltorexant in individuals with insomnia without psychiatric comorbidity.

De Boer P, Drevets WC, Rofael H, van der Ark P, Kent JM, Kezic I, Parapatics S, Dorffner G, van Gerven J, Beneš H, Keicher C, Jahn H, Seiden DJ, Luthringer R

Journal of psychopharmacology (Oxford, England), 2018 Dec; 32(6):668-677

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Valproïnezuurintoxicatie door misinterpretatie van plasmaspiegel

Roos Ruiter-Visser, Annemieke Dols, Yvo M. Smulders, Gabriel E. Jacobs en Klaas Jan Naut

Nederlands tijdschrift voor geneeskunde , 2018 Aug

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Evaluating Fitness to Perform in Surgical Residents after Night Shifts and Alcohol Intoxication: The development of a "Fit-to-Perform" test.

Huizinga CRH, de Kam ML, Stockmann HBAC, van Gerven JMA, Cohen AF, van der Bogt KEA

Journal of surgical education, 2018 Jul; 75(4):968-977

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Subanesthetic Dose Ketamine in Posttraumatic Stress Disorder: A Role for Reconsolidation During Trauma-Focused Psychotherapy?

Veen C, Jacobs G, Philippens I, Vermetten E

Current topics in behavioral neurosciences, 2018 Jun

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GSH-PEGylated liposomal methylprednisolone in comparison to free methylprednisolone: slow release characteristics and prolonged lymphocyte depression in a first-in-human study.

Kanhai KMS, Zuiker RGJA, Stavrakaki I, Gladdines W, Gaillard PJ, Klaassen ES, Groeneveld GJ

British journal of clinical pharmacology, 2018 May

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Accelerated development of the dual orexin receptor antagonist ACT-541468: Integration of a microtracer in the first-in-human study.

Muehlan C, Heuberger J, Juif PE, Croft M, van Gerven J, Dingemanse J

Clinical pharmacology and therapeutics, 2018 May

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Effect of intranasal esketamine on cognitive functioning in healthy participants: a randomized, double-blind, placebo-controlled study.

Morrison RL, Fedgchin M, Singh J, Van Gerven J, Zuiker R, Lim KS, van der Ark P, Wajs E, Xi L, Zannikos P, Drevets WC

Psychopharmacology, 2018 Apr; 235(4):1107-1119

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The Use of Physiology-Based Pharmacokinetic and Pharmacodynamic Modeling in the Discovery of the Dual Orexin Receptor Antagonist ACT-541468.

Treiber A, de Kanter R, Roch C, Gatfield J, Boss C, von Raumer M, Schindelholz B, Muehlan C, van Gerven J, Jenck F

The Journal of pharmacology and experimental therapeutics, 2018 Feb; 362(3):489-503

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Serotonergic and cholinergic modulation of functional brain connectivity: A comparison between young and older adults.

Klaassens BL, van Gerven JMA, Klaassen ES, van der Grond J, Rombouts SARB

NeuroImage, 2018 Feb

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