On 07 December 2022, Josine Vrouwe successfully defended her PhD thesis titled ‘Bone and joint disorders: Screening and early clinical drug development’ at Leiden University.
Musculoskeletal disorders have an enormous personal- and societal impact. Diagnosis and treatment of these disorders are most efficient if targeted screening, accurate diagnosis, and targeted treatment are available. To enable targeted screening, the population at risk must be well-defined and categorized if required. Subsequently, screening- and diagnostic methods must have good, or excellent predictive value and finally, treatment must target the disease, thus spare healthy tissues and processes and thereby avoid adverse events. The aim of Josine’s thesis is to gain new insights about the diagnostic process- and treatment of pathological conditions of the bone and joints, namely male urological cancer-induced bone loss and OA. Read her thesis here.
Josine was supervised by promotors Prof. dr. J. Burggraaf and Prof. dr. S. Osanto.
