Joannes Reijers did his research for his PhD thesis at CHDR on the subject 'Sticky & dirty proteins - or on the poorly characterised, peculiar, pharmacokinetic and immunostimulatory aspects of biopharmaceuticals' .This thesis addresses a couple of issues related to so-called biological therapeutics that were hitherto not explored. The research described in the thesis relate to immunogenicity and/or related side effects of therapeutic protein drugs and their remarkable pharmacokinetic behavior, We hope you enjoy this collection of work and should you wish to learn more do not hesitate to contact us.