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  • Sputum RNA signature in allergic asthmatics following allergen bronchoprovocation test.

    Zuiker RG, Tribouley C, Diamant Z, Boot JD, Cohen AF, Van Dyck K, De Lepeleire I, Rivas VM, Malkov VA, Burggraaf J, Ruddy MK

    European clinical respiratory journal, 2016 May

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  • Recombinant human pentraxin-2 therapy in patients with idiopathic pulmonary fibrosis: safety, pharmacokinetics and exploratory efficacy.

    van den Blink B, Dillingh MR, Ginns LC, Morrison LD, Moerland M, Wijsenbeek M, Trehu EG, Bartholmai BJ, Burggraaf J

    The European respiratory journal, 2016 Feb; 47(3):889-97

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  • Reproducibility of biomarkers in induced sputum and in serum from chronic smokers.

    Zuiker RG, Kamerling IM, Morelli N, Calderon C, Boot JD, de Kam M, Diamant Z, Burggraaf J, Cohen AF

    Pulmonary pharmacology & therapeutics, 2015 Jul

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  • Reversal of opioid-induced respiratory depression by BK-channel blocker GAL021: A pharmacokinetic-pharmacodynamic modeling study in healthy volunteers.

    Roozekrans M, Olofsen E, van der Schrier R, van Gerven J, Peng S, McLeod J, Dahan A

    Clinical pharmacology and therapeutics, 2015 May; 97(6):641-9

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  • Kinetics of TH2 biomarkers in sputum of asthmatics following inhaled allergen.

    Zuiker RG, Ruddy MK, Morelli N, Mogg R, Rivas VM, van Dyck K, De Lepeleire I, Tanen MR, Boot JD, Kamerling IM, Diamant Z

    European clinical respiratory journal, 2015 May

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  • Setipiprant, a selective CRTH2 antagonist, reduces allergen-induced airway responses in allergic asthmatics.

    Diamant Z, Sidharta PN, Singh D, O'Connor BJ, Zuiker R, Leaker BR, Silkey M, Dingemanse J

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2014 Aug; 44(8):1044-52

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  • Recombinant human serum amyloid P in healthy volunteers and patients with pulmonary fibrosis.

    Dillingh MR, van den Blink B, Moerland M, van Dongen MG, Levi M, Kleinjan A, Wijsenbeek MS, Lupher ML, Harper DM, Getsy JA, Hoogsteden HC, Burggraaf J

    Pulmonary pharmacology & therapeutics, 2013 Nov; 26(6):672-6

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  • Fentanyl utility function: a risk-benefit composite of pain relief and breathing responses.

    Boom M, Olofsen E, Neukirchen M, Fussen R, Hay J, Groeneveld GJ, Aarts L, Sarton E, Dahan A

    Anesthesiology, 2013 Aug; 119(3):663-74

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  • A randomized study of alglucosidase alfa in late-onset Pompe's disease.

    van der Ploeg AT, Clemens PR, Corzo D, Escolar DM, Florence J, Groeneveld GJ, Herson S, Kishnani PS, Laforet P, Lake SL, Lange DJ, Leshner RT, Mayhew JE, Morgan C, Nozaki K, Park DJ, Pestronk A, Rosenbloom B, Skrinar A, van Capelle CI, van der Beek NA, Wa

    The New England journal of medicine, 2010 Apr; 362(15):1396-406

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Browse 1079 publications in the CHDR library

  • Clinical studies & Development
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Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
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    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Engineering and Analytics
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1079 publications in the CHDR library

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