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  • The influence of personality on the sensitivity to subjective effects of Δ9-tetrahydrocannabinol.

    Kleinloog D, Stevens J, Heuberger J, Spinhoven P, van Gerven J

    Psychiatry research, 2014 Dec; 220(3):945-53

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  • The central nervous system effects of the partial GABA-Aα2,3 -selective receptor modulator AZD7325 in comparison with lorazepam in healthy males.

    Chen X, Jacobs G, de Kam M, Jaeger J, Lappalainen J, Maruff P, Smith MA, Cross AJ, Cohen A, van Gerven J

    British journal of clinical pharmacology, 2014 Nov; 78(6):1298-314

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  • Entry-into-humans study with ACT-462206, a novel dual orexin receptor antagonist, comparing its pharmacodynamics with almorexant.

    Hoch M, van Gorsel H, van Gerven J, Dingemanse J

    Journal of clinical pharmacology, 2014 Aug; 54(9):979-86

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  • Pharmacokinetic and pharmacodynamic interactions between almorexant, a dual orexin receptor antagonist, and desipramine.

    Cruz HG, Hay JL, Hoever P, Alessi F, te Beek ET, van Gerven JM, Dingemanse J

    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014 Jul; 24(8):1257-68

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  • Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ9-tetrahydrocannabinol-induced central nervous system and heart rate effects in humans.

    Klumpers LE, Roy C, Ferron G, Turpault S, Poitiers F, Pinquier JL, van Hasselt JG, Zuurman L, Erwich FA, van Gerven JM

    British journal of clinical pharmacology, 2013 Jun; 76(1):65-77

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  • Early stage development of the glycine-1 re-uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men.

    Liem-Moolenaar M, Peeters P, Kamerling IM, Hogg C, Holder G, Kleijn HJ, Spaans E, Udo De Haes J, de Kam ML, Franson KL, Cohen AF, van Gerven JM

    British journal of clinical pharmacology, 2013 May; 75(6):1455-67

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  • Determination of methylphenidate in plasma and saliva by liquid chromatography/tandem mass spectrometry.

    Seçilir A, Schrier L, Bijleveld YA, Toersche JH, Jorjani S, Burggraaf J, van Gerven J, Mathôt RA

    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013 Mar

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  • Manipulating brain connectivity with δ⁹-tetrahydrocannabinol: a pharmacological resting state FMRI study.

    Klumpers LE, Cole DM, Khalili-Mahani N, Soeter RP, Te Beek ET, Rombouts SA, van Gerven JM

    NeuroImage, 2012 Nov; 63(3):1701-11

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  • A comparison of the central nervous system effects of alcohol at pseudo-steady state in Caucasian and expatriate Japanese healthy male volunteers.

    Zoethout RW, de Kam ML, Dahan A, Cohen AF, van Gerven JM

    Alcohol (Fayetteville, N.Y.), 2012 Oct; 46(7):657-64

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Browse 1079 publications in the CHDR library

  • Clinical studies & Development
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  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Engineering and Analytics
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1079 publications in the CHDR library

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