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A two-step deconvolution-analysis-informed population pharmacodynamic modeling approach for drugs targeting pulsatile endogenous compounds.

van Esdonk MJ, Burggraaf J, van der Graaf PH, Stevens J

Journal of pharmacokinetics and pharmacodynamics, 2019 Mar; 44(4):389-400

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Population Pharmacokinetic/Pharmacodynamic Analysis of Nociceptive Pain Models Following an Oral Pregabalin Dose Administration to Healthy Subjects.

van Esdonk MJ, Lindeman I, Okkerse P, de Kam ML, Groeneveld GJ, Stevens J

CPT: pharmacometrics & systems pharmacology, 2019 Mar; 7(9):573-580

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A Novel Somatostatin-Dopamine Chimera (BIM23B065) Reduced GH Secretion in a First-in-Human Clinical Trial.

de Boon WMI, van Esdonk MJ, Stuurman FE, Biermasz NR, Pons L, Paty I, Burggraaf J

The Journal of clinical endocrinology and metabolism, 2019 Mar; 104(3):883-891

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Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability.

Mian P, van Esdonk MJ, Olkkola KT, de Winter BCM, Liukas A, Spriet I, Tibboel D, Petrovic M, Koch BCP, Allegaert K

British journal of clinical pharmacology, 2019 Jan; 85(1):126-135

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How are growth hormone and insulin-like growth factor-1 reported as markers for drug effectiveness in clinical acromegaly research? A comprehensive methodologic review

Michiel J. van Esdonk, Eline J. M. van Zutphen, Ferdinand Roelfsema, Alberto M. Pereira, Piet H. van der Graaf, Nienke R. Biermasz, Jasper Stevens, Jacobus Burggraaf

Pituitary, 2018 Mar; 21(3):310–322

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