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Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations.

Liu F, Aulin LBS, Guo T, Krekels EHJ, Moerland M, van der Graaf PH, van Hasselt JGC

British journal of clinical pharmacology, 2022 Aug

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A Randomized First-in-Human Study With UB-312, a UBITh® α-Synuclein Peptide Vaccine.

Yu HJ, Thijssen E, van Brummelen E, van der Plas JL, Radanovic I, Moerland M, Hsieh E, Groeneveld GJ, Dodart JC

Movement disorders : official journal of the Movement Disorder Society, 2022 Jul; 37(7):1416-1424

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Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?

Damman J, Mooyaart AL, Bosch TPPVD, Seelen MA, Doorn MBV

Molecular immunology, 2022 Mar

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OX40L Inhibition Suppresses KLH-driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof-of-Pharmacology for KY1005.

Saghari M, Gal P, Gilbert S, Yateman M, Porter-Brown B, Brennan N, Quaratino S, Wilson R, Grievink HW, Klaassen ES, Bergmann KR, Burggraaf J, van Doorn MBA, Powell J, Moerland M, Rissmann R

Clinical pharmacology and therapeutics, 2022 Jan

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Stimulation of the PD-1 Pathway Decreases Atherosclerotic Lesion Development in Ldlr Deficient Mice

Hendrika W. Grievink, Virginia Smit, Robin A. F. Verwilligen, Mireia N. A. Bernabé Kleijn, Diede Smeets, Christoph J. Binder, Hideo Yagita, Matthijs Moerland, Johan Kuiper, Ilze Bot and Amanda C. Foks

Front. Cardiovasc. Med., 2021 Nov

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Administration of an adeno-associated viral vector expressing interferon-β in patients with inflammatory hand arthritis, results of a phase I/II study.

Vrouwe JPM, Meulenberg JJM, Klarenbeek NB, Cañete AN, Reijnierse M, Ruiterkamp G, Bevaart L, Lamers RJ, Kloppenburg M, Nelissen RGHH, Huizinga TWJ, Burggraaf J, Kamerling IMC

Osteoarthritis and cartilage, 2021 Oct

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Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers.

Buters TP, Hameeteman PW, Jansen IME, van Hindevoort FC, Ten Voorde W, Florencia E, Osse M, de Kam ML, Grievink HW, Schoonakker M, Patel AA, Yona S, Gilroy DW, Lubberts E, Damman J, Feiss G, Rissmann R, Jansen MAA, Burggraaf J, Moerland M

British journal of clinical pharmacology, 2021 Jul

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Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19

Aliede E. in ‘t Veld, Manon A. A. Jansen, Luuk C. A. Ciere and Matthijs Moerland

2021 Mar

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Comprehensive evaluation of microneedle-based intradermal adalimumab delivery versus subcutaneous administration: results of a randomized controlled trial.

Jacobse J, Ten Voorde W, Tandon A, Romeijn SG, Grievink HW, van der Maaden K, van Esdonk MJ, Moes DJAR, Loeff F, Bloem K, de Vries A, Rispens T, Wolbink G, de Kam M, Ziagkos D, Moerland M, Jiskoot W, Bouwstra J, Burggraaf J, Schrier L, Rissmann R, Ten Cate R

British journal of clinical pharmacology, 2021 Jan

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