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Highly variable anticoagulant response after subcutaneous administration of high-dose (12,500 IU) heparin in patients with myocardial infarction and healthy volunteers.

Kroon C, ten Hove WR, de Boer A, Kroon JM, van der Pol JM, Harthoorn-Lasthuizen EJ, Schoemaker HC, van der Meer FJ, Cohen AF

Circulation, 1992 Oct; 86(5):1370-5

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Effects of temazepam on saccadic eye movements: concentration-effect relationships in individual volunteers.

van Steveninck AL, Verver S, Schoemaker HC, Pieters MS, Kroon R, Breimer DD, Cohen AF

Clinical pharmacology and therapeutics, 1992 Sep; 52(4):402-8

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Diurnal rhythm in anticoagulant effect of heparin during a low dose constant rate infusion. A study in healthy volunteers.

Krulder JW, de Boer A, van den Besselaar AM, Cohen AF, Schoemaker HC, Briët E, Meinders AE

Thrombosis and haemostasis, 1992 Jul; 68(1):30-2

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Pronounced effects of the combination of a new thromboxane antagonist (GR32191) and heparin on bleeding time in man.

de Boer A, Kroon JM, Kroon C, van Vliet A, Schoemaker HC, Breimer DD, Donoghue S, Cohen AF

Thrombosis and haemostasis, 1992 Jul; 68(1):24-9

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Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers.

Mandema JW, Tuk B, van Steveninck AL, Breimer DD, Cohen AF, Danhof M

Clinical pharmacology and therapeutics, 1992 May; 51(6):715-28

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A multicentre trial of the aldose-reductase inhibitor tolrestat, in patients with symptomatic diabetic peripheral neuropathy. North European Tolrestat Study Group.

Macleod AF, Boulton AJ, Owens DR, Van Rooy P, Van Gerven JM, Macrury S, Scarpello JH, Segers O, Heller SR, Van Der Veen EA

Diabete & metabolisme, 1992 Apr; 18(1):14-20

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Long-term effects of tolrestat on symptomatic diabetic sensory polyneuropathy.

van Gerven JM, Lemkes HH, van Dijk JG

Journal of diabetes and its complications, 1992 Apr; 6(1):45-8

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Effect of morphological abnormalities on blood retinal barrier permeability in diabetic retinopathy.

van Gerven JM, Boot JP, Lemkes HH, van Best JA

Documenta ophthalmologica. Advances in ophthalmology, 1992 Apr; 80(2):183-8

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Intraindividual variability in nifedipine pharmacokinetics and effects in healthy subjects.

Soons PA, Schoemaker HC, Cohen AF, Breimer DD

Journal of clinical pharmacology, 1992 Mar; 32(4):324-31

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