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The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • A Phase 1, Randomized, Double-blind, Placebo-controlled, Crossover Study to Evaluate the Pharmacodynamic Effects of VX-150, a highly selective NaV1.8 inhibitor, in Healthy Male Adults.

    Hijma HJH, Siebenga PSP, de Kam MLM, Groeneveld GJGJ

    Pain medicine (Malden, Mass.), 2021 Feb

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  • Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders.

    Vissers MFJM, Heuberger JAAC, Groeneveld GJ

    International journal of molecular sciences, 2021 Feb

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  • Analgesic drug development: Proof-of-mechanism and proof-of-concept in early phase clinical studies

    H.J.Hijma, G.J.Groeneveld

    Medicine in drug discovery, 2021 Feb

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  • Monitoring the recovery time of children after tonsillectomy using commercial activity trackers.

    Lambrechtse P, Ziesenitz VC, Atkinson A, Bos EJ, Welzel T, Gilgen Y, Gürtler N, Heuscher S, Cohen AF, van den Anker JN

    European journal of pediatrics, 2021 Feb; 180(2):527-533

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  • Comprehensive evaluation of microneedle-based intradermal adalimumab delivery versus subcutaneous administration: results of a randomized controlled trial.

    Jacobse J, Ten Voorde W, Tandon A, Romeijn SG, Grievink HW, van der Maaden K, van Esdonk MJ, Moes DJAR, Loeff F, Bloem K, de Vries A, Rispens T, Wolbink G, de Kam M, Ziagkos D, Moerland M, Jiskoot W, Bouwstra J, Burggraaf J, Schrier L, Rissmann R, Ten Cate R

    British journal of clinical pharmacology, 2021 Jan

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  • Experience in Genetic Counseling for Variants in Parkinson's Disease.

    den Heijer JM, van Hilten JJ, Kievit AJA, Bonifati V, Groeneveld GJ

    Movement disorders clinical practice, 2021 Jan; 8(1):33-36

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  • First-in-man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M -receptor partial agonist for the treatment of dementias.

    Bakker C, Tasker T, Liptrot J, Hart EP, Klaassen ES, Prins S, van der Doef TF, Brown GA, Brown A, Congreve M, Weir M, Marshall FH, Cross DM, Groeneveld GJ, Nathan PJ

    British journal of clinical pharmacology, 2020 Dec

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  • Assessment of risks associated with SARS-CoV-2 experimental human infection studies.

    Kuiper VP, Rosendaal FR, Kamerling IMC, Visser LG, Roestenberg M

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Nov

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  • Proof of pharmacology of Org 48775-0, a p38 MAP kinase inhibitor, in healthy volunteers.

    Moerland M, Kales AJ, Broekhuizen K, Nässander U, Nelissen R, de Kam ML, Peeters PAM, Burggraaf J

    British journal of clinical pharmacology, 2020 Nov

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Browse 969 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-Inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- & microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessements
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac & Endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Pharmacokinetics and pharmacometrics
    • CHDR Cardiology
    • Biomarker Laboratory
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 969 publications in the CHDR library

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