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  • Comparative effects of felodipine, nitrendipine and nifedipine in healthy subjects: concentration-effect relationships of racemic drugs and enantiomers.

    Soons PA, Cohen AF, Breimer DD

    European journal of clinical pharmacology, 1993 Apr; 44(2):113-20

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  • Stereoselective pharmacokinetics of oral felodipine and nitrendipine in healthy subjects: correlation with nifedipine pharmacokinetics.

    Soons PA, Mulders TM, Uchida E, Schoemaker HC, Cohen AF, Breimer DD

    European journal of clinical pharmacology, 1993 Apr; 44(2):163-9

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  • CNS-related performance and haemodynamics of metoprolol-Oros and propranolol after single and 3 days dosing in healthy volunteers.

    van Steveninck AL, Pieters MS, Schoemaker HC, Breimer DD, Cohen AF

    British journal of clinical pharmacology, 1993 Jan; 35(2):114-20

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  • The bioavailability of digoxin from three oral formulations measured by a specific h.p.l.c. assay.

    Cohen AF, Kroon R, Schoemaker HC, Breimer DD, Van Vliet-Verbeek A, Brandenburg HC

    British journal of clinical pharmacology, 1993 Jan; 35(2):136-42

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  • Characterization of glutathione conjugation in humans: stereoselectivity in plasma elimination pharmacokinetics and urinary excretion of (R)- and (S)-2-bromoisovalerylurea in healthy volunteers.

    Mulders TM, Venizelos V, Schoemaker R, Cohen AF, Breimer DD, Mulder GJ

    Clinical pharmacology and therapeutics, 1992 Dec; 53(1):49-58

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  • Influence of heparin and a low molecular weight heparinoid on specific endogenous and exogenous fibrinolytic factors during rest and exercise.

    de Boer A, Kluft C, Dooijewaard G, Kasper FJ, Kroon JM, Breimer DD, Stiekema JC, Cohen AF

    Thrombosis and haemostasis, 1992 Nov; 68(5):550-5

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  • Highly variable anticoagulant response after subcutaneous administration of high-dose (12,500 IU) heparin in patients with myocardial infarction and healthy volunteers.

    Kroon C, ten Hove WR, de Boer A, Kroon JM, van der Pol JM, Harthoorn-Lasthuizen EJ, Schoemaker HC, van der Meer FJ, Cohen AF

    Circulation, 1992 Oct; 86(5):1370-5

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  • Effects of temazepam on saccadic eye movements: concentration-effect relationships in individual volunteers.

    van Steveninck AL, Verver S, Schoemaker HC, Pieters MS, Kroon R, Breimer DD, Cohen AF

    Clinical pharmacology and therapeutics, 1992 Sep; 52(4):402-8

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  • Diurnal rhythm in anticoagulant effect of heparin during a low dose constant rate infusion. A study in healthy volunteers.

    Krulder JW, de Boer A, van den Besselaar AM, Cohen AF, Schoemaker HC, Briët E, Meinders AE

    Thrombosis and haemostasis, 1992 Jul; 68(1):30-2

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Browse 1016 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1016 publications in the CHDR library

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