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The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • Brain Bio-Energetic State Does Not Correlate to Muscle Mitochondrial Function in Huntington's Disease.

    van Diemen MPJ, Hart EP, Hameeteman PW, Coppen EM, Winder JY, den Heijer J, Moerland M, Kan H, van der Grond J, Webb A, Roos RAC, Groeneveld GJ

    Journal of Huntington's disease, 2021 Jun; 9(4):335-344

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  • Safety and Pharmacokinetics of HTL0018318, a Novel M Receptor Agonist, Given in Combination with Donepezil at Steady State: A Randomized Trial in Healthy Elderly Subjects.

    Bakker C, van der Aart J, Labots G, Liptrot J, Cross DM, Klaassen ES, Dickinson S, Tasker T, Groeneveld GJ

    Drugs in R&D, 2021 Jun

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  • Quantitative dynamic near-infrared fluorescence imaging using indocyanine green for analysis of bowel perfusion after mesenteric resection

    Ruben P. J. Meijer, Labrinus van Manen, Henk H. Hartgrink, Jacobus Burggraaf, Sylvain Gioux, Alexander L. Vahrmeijer, J. Sven D. Mieog

    Journal of Biomedical Optics, 2021 Jun

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  • A Study of Novel Exploratory Tools, Digital Technologies, and Central Nervous System Biomarkers to Characterize Unipolar Depression.

    Sverdlov O, Curcic J, Hannesdottir K, Gou L, De Luca V, Ambrosetti F, Zhang B, Praestgaard J, Vallejo V, Dolman A, Gomez-Mancilla B, Biliouris K, Deurinck M, Cormack F, Anderson JJ, Bott NT, Peremen Z, Issachar G, Laufer O, Joachim D, Jagesar RR, Jongs N, Kas MJ, Zhuparris A, Zuiker R, Recourt K, Zuilhof Z, Cha JH, Jacobs GE

    Frontiers in psychiatry, 2021 Jun

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  • Assessment of fitness to perform using a validated self-test in obstetric and gynecological night shifts in the Netherlands.

    Tummers FHMP, Huizinga CRH, van Pampus MG, Stockmann HBAC, Cohen AF, van der Bogt KEA,

    American journal of obstetrics and gynecology, 2021 Jun; 224(6):617.e1-617.e14

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  • First-in-human trial to assess safety, tolerability, pharmacokinetics and pharmacodynamics of STR-324, a dual enkephalinase inhibitor for pain management.

    Moss LM, Berends CL, van Brummelen EMJ, Kamerling IMC, Klaassen ES, Bergmann K, Ville V, Juarez-Perez V, Benichou AC, Groeneveld GJ

    British journal of clinical pharmacology, 2021 May

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  • Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation

    Patricio O’Donnell, Francis M. Dijkstra, Ugur Damar, Lei Quanhong, Annika A. de Goede, Lin Xu, Andres Pascual-Leone, Derek L. Buhl, Rob Zuiker, Titia Q. Ruijs, Jules A. A. C. Heuberger, Paul MacMullin, Martin Lubell, Mahnaz Asgharnejad, Venkatesha Murthy, Alexander Rotenberg, Gabriel E. Jacobs & Laura Rosen

    Translational Psychiatry, 2021 May

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  • Drug Clearance in Neonates: A Combination of Population Pharmacokinetic Modelling and Machine Learning Approaches to Improve Individual Prediction.

    Tang BH, Guan Z, Allegaert K, Wu YE, Manolis E, Leroux S, Yao BF, Shi HY, Li X, Huang X, Wang WQ, Shen AD, Wang XL, Wang TY, Kou C, Xu HY, Zhou Y, Zheng Y, Hao GX, Xu BP, Thomson AH, Capparelli EV, Biran V, Simon N, Meibohm B, Lo YL, Marques R, Peris JE, Lutsar I, Saito J, Burggraaf J, Jacqz-Aigrain E, van den Anker J, Zhao W

    Clinical pharmacokinetics, 2021 May

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  • Biperiden Challenge Model in Healthy Elderly as Proof-of-pharmacology Tool; A Randomized Placebo-controlled Trial.

    Bakker C, van Esdonk MJ, Stuurman RFE, Borghans LAGJM, de Kam ML, van Gerven JMA, Groeneveld GJ

    Journal of clinical pharmacology, 2021 May

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Browse 965 publications in the CHDR library

  • Clinical studies & Development
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Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-Inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- & microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessements
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac & Endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Pharmacokinetics and pharmacometrics
    • CHDR Cardiology
    • Biomarker Laboratory
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 965 publications in the CHDR library

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