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A randomized Phase 2 study to evaluate the orexin-2 receptor antagonist seltorexant in individuals with insomnia without psychiatric comorbidity.

De Boer P, Drevets WC, Rofael H, van der Ark P, Kent JM, Kezic I, Parapatics S, Dorffner G, van Gerven J, Beneš H, Keicher C, Jahn H, Seiden DJ, Luthringer R

Journal of psychopharmacology (Oxford, England), 2018 Dec; 32(6):668-677

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Clearance of plasminogen activator--a major determinant of plasma concentration: therapeutic and diagnostic implications.

Cohen AF, Burggraaf K, de Boer A, Kluft C

Annals of the New York Academy of Sciences, 2018 Dec

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Assessment of changes in liver blood flow after food intake--comparison of ICG clearance and echo-Doppler.

Burggraaf J, Schoemaker HC, Cohen AF

British journal of clinical pharmacology, 2018 Dec; 42(4):499-502

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Effects of two antihistamine drugs on actual driving performance.

Cohen AF, Posner J

British medical journal (Clinical research ed.), 2018 Dec; 288(6421):935

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Human immunodeficiency virus--associated non-Hodgkin's lymphoma presenting as an auricular perichondritis.

Levin RJ, Henick DH, Cohen AF

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2018 Dec; 112(3):493-5

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Evidence of NI-0101 pharmacological activity, an anti-TLR4 antibody, in a randomized phase I dose escalation study in healthy volunteers receiving LPS.

Monnet E, Lapeyre G, Poelgeest EV, Jacqmin P, Graaf K, Reijers J, Moerland M, Burggraaf J, Min C

Clinical pharmacology and therapeutics, 2018 Dec; 101(2):200-208

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A comparison of methods for assessing the sedative effects of diphenhydramine on skills related to car driving.

Cohen AF, Posner J, Ashby L, Smith R, Peck AW

European journal of clinical pharmacology, 2018 Dec; 27(4):477-82

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Validation of a pharmacological model for mitochondrial dysfunction in healthy subjects using simvastatin: A randomized placebo-controlled proof-of-pharmacology study.

van Diemen MPJ, Berends CL, Akram N, Wezel J, Teeuwisse WM, Mik BG, Kan HE, Webb A, Beenakker JWM, Groeneveld GJ

European journal of pharmacology, 2018 Dec

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Acute Effects of Riluzole and Retigabine on Axonal Excitability in Patients With Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial.

Kovalchuk MO, Heuberger JAAC, Sleutjes BTHM, Ziagkos D, van den Berg LH, Ferguson TA, Franssen H, Groeneveld GJ

Clinical pharmacology and therapeutics, 2018 Dec; 104(6):1136-1145

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