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Multiple-dose clinical pharmacology of ACT-541468, a novel dual orexin receptor antagonist, following repeated-dose morning and evening administration.

Muehlan C, Brooks S, Zuiker R, van Gerven J, Dingemanse J

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2019 Jul; 29(7):847-857

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Spotlight Commentary: How to prove pharmacology of immunomodulatory drugs in a phase 1 trial?

Rissmann R, Szabadi E

British journal of clinical pharmacology, 2019 Jun; 85(7):1389-1390

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Effect of Food on the Pharmacokinetics of 2 Formulations of DRL-17822, a Novel Selective Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Males.

Kruithof AC, Kumar R, Stevens J, de Kam ML, Gautam A, Alikunju S, Padhi BK, Kulkarni S, Raghuvanshi RS, Gandhi R, Burggraaf J, Kamerling IMC

Clinical pharmacology in drug development, 2019 Jun

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Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index.

Hassing GJ, van der Wall HEC, van Westen GJP, Kemme MJB, Adiyaman A, Elvan A, Burggraaf J, Gal P

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2019 May

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Human pharmacology of positive GABA-A subtype-selective receptor modulators for the treatment of anxiety.

Chen X, van Gerven J, Cohen A, Jacobs G

Acta pharmacologica Sinica, 2019 May; 40(5):571-582

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Spotlight Commentary: A post approval look at anticoagulants.

Wei L, Cohen A, de Boer T

British journal of clinical pharmacology, 2019 Apr; 85(7):1394-1395

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A review of current approaches for evaluating impaired performance in around-the-clock medical professionals.

Huizinga CRH, Tummers FHMP, Marang-van de Mheen PJ, Cohen AF, van der Bogt KEA

Sleep medicine reviews, 2019 Apr

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Evaluation of simulated driving in comparison to laboratory-based tests to assess the pharmacodynamics of alprazolam and alcohol.

Huizinga CR, Zuiker RG, de Kam ML, Ziagkos D, Kuipers J, Mejia Y, van Gerven JM, Cohen AF

Journal of psychopharmacology (Oxford, England), 2019 Apr

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Effect of short-term fasting on electrocardiographic parameters.

van der Stuijt W, Gal P, Kemme MJB, Burggraaf J

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2019 Apr

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