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Pharmacokinetics and Pharmacodynamics of the Dual Orexin Receptor Antagonist Daridorexant in Japanese and Caucasian Subjects

Muehlan C, Zuiker R, Peeters P, Rowles R, Dingemanse J

Journal of clinical psychopharmacology, 2020 Mar; 40(2):157-166

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Model informed quantification of the feed-forward stimulation of growth hormone by growth hormone-releasing hormone.

van Esdonk MJ, Burggraaf J, van der Graaf PH, Stevens J

British journal of clinical pharmacology, 2020 Mar

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Glucocerebrosidase: Functions in and Beyond the Lysosome.

Boer DEC, van Smeden J, Bouwstra JA, Aerts JMFG

Journal of clinical medicine, 2020 Mar

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Omiganan Enhances Imiquimod-Induced Inflammatory Responses in Skin of Healthy Volunteers.

Niemeyer-van der Kolk T, Assil S, Buters TP, Rijsbergen M, Klaassen ES, Feiss G, Florencia E, Prens EP, Burggraaf J, van Doorn MBA, Rissmann R, Moerland M

Clinical and translational science, 2020 Mar

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Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration.

Muehlan C, Boehler M, Brooks S, Zuiker R, van Gerven J, Dingemanse J

Journal of psychopharmacology (Oxford, England), 2020 Mar

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Skin of atopic dermatitis patients shows disturbed β-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition.

Boer DEC, van Smeden J, Al-Khakany H, Melnik E, van Dijk R, Absalah S, Vreeken RJ, Haenen CCP, Lavrijsen APM, Overkleeft HS, Aerts JMFG, Bouwstra JA

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020 Feb; 1865(6):158673

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Simultaneous tracking of psychophysical detection thresholds and evoked potentials to study nociceptive processing.

van den Berg B, Doll RJ, Mentink ALH, Siebenga PS, Groeneveld GJ, Buitenweg JR

Behavior research methods, 2020 Jan

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Potential targets for tumor-specific imaging of vulvar squamous cell carcinoma: A systematic review of candidate biomarkers.

Huisman BW, Burggraaf J, Vahrmeijer AL, Schoones JW, Rissmann RA, Sier CFM, van Poelgeest MIE

Gynecologic oncology, 2020 Jan

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Pain-related changes in cutaneous innervation of patients suffering from bortezomib-induced, diabetic or chronic idiopathic axonal polyneuropathy.

Bechakra M, Nieuwenhoff MD, Rosmalen JV, Jan Groeneveld G, J P M Huygen F, Zeeuw CI, Doorn PAV, Jongen JLM

Brain research, 2020 Jan

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