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Lack of Detection of the Analgesic Properties of PF-05089771, a Selective Na 1.7 Inhibitor, Using a Battery of Pain Models in Healthy Subjects.

Siebenga P, van Amerongen G, Hay JL, McDonnell A, Gorman D, Butt R, Groeneveld GJ

Clinical and translational science, 2019 Oct

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Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration.

Muehlan C, Boehler M, Brooks S, Zuiker R, van Gerven J, Dingemanse J

Journal of psychopharmacology (Oxford, England), 2019 Oct

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Pharmacogenetic interactions in amyotrophic lateral sclerosis: a step closer to a cure?

van Eijk RPA, Eijkemans MJC, Nikolakopoulos S, Jansen MD, Westeneng HJ, van Eijk KR, van der Spek RAA, van Vugt JJFA, Piepers S, Groeneveld GJ, Veldink JH, van den Berg LH, van Es MA

The pharmacogenomics journal, 2019 Oct

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Mathematical modeling of the glucagon challenge test

Saeed Masroor, Marloes G. J. van Dongen, Ricardo Alvarez-Jimenez, Koos Burggraaf, Lambertus A. Peletier, Mark A. Peletier

2019 Oct

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Fluctuations in Pharmacokinetics Profiles of Monoclonal Antibodies.

Grabowski T, Reijers JAA, Burmańczuk A, Chełmońska-Soyta A

European journal of drug metabolism and pharmacokinetics, 2019 Oct; 44(5):585-589

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Cholinergic and serotonergic modulation of resting state functional brain connectivity in Alzheimer's disease.

Klaassens BL, van Gerven JMA, Klaassen ES, van der Grond J, Rombouts SARB

NeuroImage, 2019 Oct

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Immunomonitoring of Tacrolimus in Healthy Volunteers: The First Step from PK- to PD-Based Therapeutic Drug Monitoring?

In 't Veld AE, Grievink HW, Saghari M, Stuurman FE, de Kam ML, de Vries APJ, de Winter BCM, Burggraaf J, Cohen AF, Moerland M

International journal of molecular sciences, 2019 Sep

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The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder

Kasper Recourt, Peter de Boer, Rob Zuiker, Remy Luthringer, Justine Kent, Peter van der Ark, Ilse Van Hove, Joop van Gerven, Gabriel Jacobs, Luc van Nueten and Wayne Drevets

2019 Sep

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Rare disease specialists and clinical pharmacologists unite: Increase collection of longitudinal data!

Santen GWE, Cohen AF

British journal of clinical pharmacology, 2019 Sep

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