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Pharmacodynamics of temazepam in primary insomnia: assessment of the value of quantitative electroencephalography and saccadic eye movements in predicting improvement of sleep.

Tuk B, Oberyé JJ, Pieters MS, Schoemaker RC, Kemp B, van Gerven J, Danhof M, Kamphuisen HA, Cohen AF, Breimer DD, Peck CC

Clinical pharmacology and therapeutics, 1997 Oct; 62(4):444-52

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The sensitivity of pharmacodynamic tests for the central nervous system effects of drugs on the effects of sleep deprivation.

van Steveninck AL, van Berckel BN, Schoemaker RC, Breimer DD, van Gerven JM, Cohen AF

Journal of psychopharmacology (Oxford, England), 1999 Aug; 13(1):10-7

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Multiple-dose clinical pharmacology of ACT-541468, a novel dual orexin receptor antagonist, following repeated-dose morning and evening administration.

Muehlan C, Brooks S, Zuiker R, van Gerven J, Dingemanse J

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2019 Jul; 29(7):847-857

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Accelerated development of the dual orexin receptor antagonist ACT-541468: Integration of a microtracer in the first-in-human study.

Muehlan C, Heuberger J, Juif PE, Croft M, van Gerven J, Dingemanse J

Clinical pharmacology and therapeutics, 2018 May

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Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration.

Muehlan C, Boehler M, Brooks S, Zuiker R, van Gerven J, Dingemanse J

Journal of psychopharmacology (Oxford, England), 2020 Mar

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Central nervous system effects of the histamine-3 receptor antagonist CEP-26401, in comparison with modafinil and donepezil, after a single dose in a cross-over study in healthy volunteers.

Baakman AC, Zuiker R, van Gerven JMA, Gross N, Yang R, Fetell M, Gershon A, Gilgun-Sherki Y, Hellriegel E, Spiegelstein O

British journal of clinical pharmacology, 2019 Mar

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Promotion of sleep by targeting the orexin system in rats, dogs and humans.

Brisbare-Roch C, Dingemanse J, Koberstein R, Hoever P, Aissaoui H, Flores S, Mueller C, Nayler O, van Gerven J, de Haas SL, Hess P, Qiu C, Buchmann S, Scherz M, Weller T, Fischli W, Clozel M, Jenck F

Nature medicine, 2007 Jan; 13(2):150-5

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Exploratory polysomnographic evaluation of pregabalin on sleep disturbance in patients with epilepsy.

de Haas S, Otte A, de Weerd A, van Erp G, Cohen A, van Gerven J

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2007 Aug; 3(5):473-8

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Guidelines for the recording and evaluation of pharmaco-sleep studies in man: the International Pharmaco-EEG Society (IPEG).

Jobert M, Wilson FJ, Roth T, Ruigt GS, Anderer P, Drinkenburg WH, Bes FW, Brunovsky M, Danker-Hopfe H, Freeman J, van Gerven JM, Gruber G, Kemp B, Klösch G, Ma J, Penzel T, Peterson BT, Schulz H, Staner L, Saletu B, Svetnik V,

Neuropsychobiology, 2013 Mar; 67(3):127-67

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