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  • Relationship between airway responsiveness to neurokinin A and methacholine in asthma.

    Cohen J, Burggraaf J, Schoemaker RC, Sterk PJ, Cohen AF, Diamant Z

    Pulmonary pharmacology & therapeutics, 2005 Mar; 18(3):171-6

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  • Pharmacokinetics of intravenous and inhaled salbutamol and tobramycin: an exploratory study to investigate the potential of exhaled breath condensate as a matrix for pharmacokinetic analysis.

    Kruizinga MD, Birkhoff WAJ, van Esdonk MJ, Klarenbeek NB, Cholewinski T, Nelemans T, Dröge MJ, Cohen AF, Zuiker RGJA

    British journal of clinical pharmacology, 2019 Nov

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  • Sputum RNA signature in allergic asthmatics following allergen bronchoprovocation test.

    Zuiker RG, Tribouley C, Diamant Z, Boot JD, Cohen AF, Van Dyck K, De Lepeleire I, Rivas VM, Malkov VA, Burggraaf J, Ruddy MK

    European clinical respiratory journal, 2016 May

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  • Effect of an NK1/NK2 receptor antagonist on airway responses and inflammation to allergen in asthma.

    Boot JD, de Haas S, Tarasevych S, Roy C, Wang L, Amin D, Cohen J, Sterk PJ, Miller B, Paccaly A, Burggraaf J, Cohen AF, Diamant Z

    American journal of respiratory and critical care medicine, 2007 Feb; 175(5):450-7

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  • Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials.

    Franciosi LG, Diamant Z, Banner KH, Zuiker R, Morelli N, Kamerling IM, de Kam ML, Burggraaf J, Cohen AF, Cazzola M, Calzetta L, Singh D, Spina D, Walker MJ, Page CP

    The Lancet. Respiratory medicine, 2018 Aug; 1(9):714-27

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  • Reversal of the late asthmatic response increases exhaled nitric oxide.

    Boot JD, Tarasevych S, Sterk PJ, Schoemaker RC, Wang L, Amin D, Cohen AF, Diamant Z

    Respiratory medicine, 2005 Nov; 99(12):1591-4

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  • Reproducibility of biomarkers in induced sputum and in serum from chronic smokers.

    Zuiker RG, Kamerling IM, Morelli N, Calderon C, Boot JD, de Kam M, Diamant Z, Burggraaf J, Cohen AF

    Pulmonary pharmacology & therapeutics, 2015 Jul

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  • Nasal nitric oxide: longitudinal reproducibility and the effects of a nasal allergen challenge in patients with allergic rhinitis.

    Boot JD, de Kam ML, Mascelli MA, Miller B, van Wijk RG, de Groot H, Cohen AF, Diamant Z

    Allergy, 2007 Mar; 62(4):378-84

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  • MK-0873, a PDE4 inhibitor, does not influence the pharmacokinetics of theophylline in healthy male volunteers.

    Boot JD, De Haas SL, Van Gerven JM, De Smet M, Leathem T, Wagner J, Denker A, Miller D, Van Doorn MB, Schoemaker RC, Cohen AF, Diamant Z

    Pulmonary pharmacology & therapeutics, 2008 Apr; 21(3):573-7

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Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
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    • Sleep disorders

    Internal Medicine

    • Biologicals
    • Coagulation
    • Dermatology
    • Endocrinology
    • Immunology & Inflammation
    • Pulmonology
    • Vascular Medicine
  • Methods & Biomarkers

    Central Nervous System

    • CO2 inhalation challenge
    • Driving Performance
    • Ethanol interaction
    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • Transcranial Magnetic Stimulation (TMS)

    Internal Medicine

    • Cardiac & Endovascular function assessments
    • Dermatological assessements
    • Inflammatory challenges
    • Metabolic and endocrine responses
    • Pulmonary function tests

    Imaging Techniques

    • Image-guided surgery
    • PET Imaging
    • fMRI

    Translational Biomarkers

    • Cell cultures and incubations/challenges
    • Immunophenotyping
    • Isolation of primary human cells
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • CHDR Cardiology
    • Biomarker Laboratory
    • Data Management
    CHDR InnoS
    Participate in a Clinical Trial proefpersoon.nl

Browse 751 publications in the CHDR library

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