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Phase 1 Clinical Trial of Losmapimod in Facioscapulohumeral Dystrophy (FSHD): Safety, Tolerability, Pharmacokinetics, and Target Engagement.

Mellion ML, Ronco L, Berends CL, Pagan L, Brooks S, van Esdonk MJ, van Brummelen EMJ, Odueyungbo A, Thompson LA, Hage M, Badrising UA, Raines S, Tracewell WG, van Engelen B, Cadavid D, Groeneveld GJ

British journal of clinical pharmacology, 2021 Apr

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Cholinergic and serotonergic modulation of resting state functional brain connectivity in Alzheimer's disease.

Klaassens BL, van Gerven JMA, Klaassen ES, van der Grond J, Rombouts SARB

NeuroImage, 2019 Oct

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Validation of a pharmacological model for mitochondrial dysfunction in healthy subjects using simvastatin: A randomized placebo-controlled proof-of-pharmacology study.

van Diemen MPJ, Berends CL, Akram N, Wezel J, Teeuwisse WM, Mik BG, Kan HE, Webb A, Beenakker JWM, Groeneveld GJ

European journal of pharmacology, 2018 Dec

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Diminished Posterior Precuneus Connectivity with the Default Mode Network Differentiates Normal Aging from Alzheimer's Disease.

Klaassens BL, van Gerven JMA, van der Grond J, de Vos F, Möller C, Rombouts SARB

Frontiers in aging neuroscience, 2018 Feb

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Serotonergic and cholinergic modulation of functional brain connectivity: A comparison between young and older adults.

Klaassens BL, van Gerven JMA, Klaassen ES, van der Grond J, Rombouts SARB

NeuroImage, 2018 Feb

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Biomarkers, designs, and interpretations of resting-state fMRI in translational pharmacological research: A review of state-of-the-Art, challenges, and opportunities for studying brain chemistry.

Khalili-Mahani N, Rombouts SA, van Osch MJ, Duff EP, Carbonell F, Nickerson LD, Becerra L, Dahan A, Evans AC, Soucy JP, Wise R, Zijdenbos AP, van Gerven JM

Human brain mapping, 2018 Feb; 38(4):2276-2325

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Time related effects on functional brain connectivity after serotonergic and cholinergic neuromodulation.

Klaassens BL, Rombouts SA, Winkler AM, van Gorsel HC, van der Grond J, van Gerven JM

Human brain mapping, 2016 Dec; 38(1):308-325

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Subjective Effects of Ethanol, Morphine, Δ(9)-Tetrahydrocannabinol, and Ketamine Following a Pharmacological Challenge Are Related to Functional Brain Connectivity.

Kleinloog D, Rombouts S, Zoethout R, Klumpers L, Niesters M, Khalili-Mahani N, Dahan A, van Gerven J

Brain connectivity, 2015 Nov; 5(10):641-8

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Single-dose serotonergic stimulation shows widespread effects on functional brain connectivity.

Klaassens BL, van Gorsel HC, Khalili-Mahani N, van der Grond J, Wyman BT, Whitcher B, Rombouts SA, van Gerven JM

NeuroImage, 2015 Nov

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