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  • Multi-parameter comparison of a standardized mixed meal tolerance test in healthy and type 2 diabetic subjects: the PhenFlex challenge.

    Wopereis S, Stroeve JHM, Stafleu A, Bakker GCM, Burggraaf J, van Erk MJ, Pellis L, Boessen R, Kardinaal AAF, van Ommen B

    Genes & nutrition, 2018 May

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  • Renal Effects of Antisense-Mediated Inhibition of SGLT2.

    van Meer L, Moerland M, van Dongen M, Goulouze B, de Kam M, Klaassen E, Cohen A, Burggraaf J

    The Journal of pharmacology and experimental therapeutics, 2016 Oct; 359(2):280-289

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  • A single infusion of MDCO-216 (ApoA-1 Milano/POPC) increases ABCA1-mediated cholesterol efflux and pre-beta 1 HDL in healthy volunteers and patients with stable coronary artery disease.

    Kallend DG, Reijers JA, Bellibas SE, Bobillier A, Kempen H, Burggraaf J, Moerland M, Wijngaard PL

    European heart journal. Cardiovascular pharmacotherapy, 2015 Dec; 2(1):23-9

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  • Antisense-mediated reduction of proprotein convertase subtilisin/kexin type 9 (PCSK9): a first-in-human randomized, placebo-controlled trial.

    van Poelgeest EP, Hodges MR, Moerland M, Tessier Y, Levin AA, Persson R, Lindholm MW, Dumong Erichsen K, Ørum H, Cohen AF, Burggraaf J

    British journal of clinical pharmacology, 2015 Nov; 80(6):1350-61

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  • First proof of pharmacology in humans of a novel glucagon receptor antisense drug.

    van Dongen MG, Geerts BF, Morgan ES, Brandt TA, de Kam ML, Romijn JA, Cohen AF, Bhanot S, Burggraaf J

    Journal of clinical pharmacology, 2015 Feb; 55(3):298-306

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  • Changes in bone mineral density in newly diagnosed testicular cancer patients after anticancer treatment.

    Willemse PM, Hamdy NA, de Kam ML, Burggraaf J, Osanto S

    The Journal of clinical endocrinology and metabolism, 2014 Oct; 99(11):4101-8

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  • Midazolam pharmacokinetics in morbidly obese patients following semi-simultaneous oral and intravenous administration: a comparison with healthy volunteers.

    Brill MJ, van Rongen A, Houwink AP, Burggraaf J, van Ramshorst B, Wiezer RJ, van Dongen EP, Knibbe CA

    Clinical pharmacokinetics, 2014 Sep; 53(10):931-41

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  • Characterization of a standardized glucagon challenge test as a pharmacodynamic tool in pharmacological research.

    van Dongen MG, Geerts BF, Bhanot S, Morgan ES, de Kam ML, Moerland M, Romijn JA, Cohen AF, Burggraaf J

    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2014 Mar; 46(4):269-73

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  • Comparison of body surface area versus weight-based growth hormone dosing for girls with Turner syndrome.

    Schrier L, de Kam ML, McKinnon R, Che Bakri A, Oostdijk W, Sas TC, Menke LA, Otten BJ, de Muinck Keizer-Schrama SM, Kristrom B, Ankarberg-Lindgren C, Burggraaf J, Albertsson-Wikland K, Wit JM

    Hormone research in paediatrics, 2014 Mar; 81(5):319-30

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Browse 1148 publications in the CHDR library

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Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
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    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Engineering and Analytics
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1148 publications in the CHDR library

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