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Ex vivo fluorescence-guided resection margin assessment in breast cancer surgery using a topically applied, cathepsin-activatable imaging agent.

Linders DGJ, Bijlstra OD, Walker E, March TL, Pool M, Valentijn ARPM, Dijkhuis TH, Woltering JN, Pijl FR, Noordam G, van den Burg D, van der Sijp JRM, Guicherit OR, Marinelli AWKS, Burggraaf J, Rissmann R, Bogyo M, Hilling DE, Kuppen PJK, Straight B, Straver ME, Hazelbag HM, Basilion JP, Vahrmeijer AL

Pharmacological research, 2024 Oct

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Preclinical evaluation of EpCAM-binding designed ankyrin repeat proteins (DARPins) as targeting moieties for bimodal near-infrared fluorescence and photoacoustic imaging of cancer.

Houvast RD, Badr N, March T, de Muynck LDAN, Sier VQ, Schomann T, Bhairosingh S, Baart VM, Peeters JAHM, van Westen GJP, Plückthun A, Burggraaf J, Kuppen PJK, Vahrmeijer AL, Sier CFM

European journal of nuclear medicine and molecular imaging, 2023 Aug

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First-in-patient study of OTL78 for intraoperative fluorescence imaging of prostate-specific membrane antigen-positive prostate cancer: a single-arm, phase 2a, feasibility trial.

Stibbe JA, de Barros HA, Linders DGJ, Bhairosingh SS, Bekers EM, van Leeuwen PJ, Low PS, Kularatne SA, Vahrmeijer AL, Burggraaf J, van der Poel HG

The Lancet. Oncology, 2023 May; 24(5):457-467

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Data-Driven Identification of Targets for Fluorescence-Guided Surgery in Non-Small Cell Lung Cancer.

Meijer RPJ, Neijenhuis LKA, Zeilstra AP, Roerink SF, Bhairosingh SS, Hilling DE, Mieog JSD, Kuppen PJK, Sier CFM, Braun J, Burggraaf J, Vahrmeijer AL, Cohen D, Hutteman M

Molecular imaging and biology, 2023 Feb; 25(1):228-239

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Cysteine Cathepsins in Breast Cancer: Promising Targets for Fluorescence-Guided Surgery.

Linders DGJ, Bijlstra OD, Fallert LC, Hilling DE, Walker E, Straight B, March TL, Valentijn ARPM, Pool M, Burggraaf J, Basilion JP, Vahrmeijer AL, Kuppen PJK

Molecular imaging and biology, 2022 Aug

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Highlighting the Undetectable - Fluorescence Molecular Imaging in Gastrointestinal Endoscopy.

Stibbe JA, Hoogland P, Achterberg FB, Holman DR, Sojwal RS, Burggraaf J, Vahrmeijer AL, Nagengast WB, Rogalla S

Molecular imaging and biology, 2022 Jun

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AVOID; a phase III, randomised controlled trial using indocyanine green for the prevention of anastomotic leakage in colorectal surgery.

Meijer RPJ, Faber RA, Bijlstra OD, Braak JPBM, Meershoek-Klein Kranenbarg E, Putter H, Mieog JSD, Burggraaf K, Vahrmeijer AL, Hilling DE,

BMJ open, 2022 Apr; 12(4):e051144

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Near-Infrared Fluorescence Tumor-Targeted Imaging in Lung Cancer: A Systematic Review

Lisanne K. A. Neijenhuis, Lysanne D. A. N. de Myunck , Okker D. Bijlstra , Peter J. K. Kuppen , Denise E. Hilling , Frank J. Borm, Danielle Cohen, J. Sven D. Mieog, Willem H. Steup , Jerry Braun, Jacobus Burggraaf, Alexander L. Vahrmeijer and Merlijn Hutteman

Life, 2022 Mar

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Near-Infrared Fluorescence Tumor-Targeted Imaging in Lung Cancer: A Systematic Review.

Neijenhuis LKA, de Myunck LDAN, Bijlstra OD, Kuppen PJK, Hilling DE, Borm FJ, Cohen D, Mieog JSD, Steup WH, Braun J, Burggraaf J, Vahrmeijer AL, Hutteman M

Life (Basel, Switzerland), 2022 Mar

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