Key publication
155
Psychiatry
Methods & challenges

Key publication

A smartphone- and wearable-based biomarker for the estimation of unipolar depression severity.

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Item response theory in early phase clinical trials: Utilization of a reference model to analyze the Montgomery-Ã…sberg Depression Rating Scale.

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Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder.

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Fit for purpose of on-the-road driving and simulated driving: A randomised crossover study using the effect of sleep deprivation.

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Cognitive performance in healthy clinical trial participants and patients with the NeuroCart, a neurodegenerative disease measured with an automated neuropsychological and neurophysiological test battery.

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Decreased integrity of the monoaminergic tract is associated with a positive response to MPH in patients with vascular cognitive impairment - proof of principle study STREAM-VCI.

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Pharmacological characterization of the selective orexin-1 receptor antagonist JNJ-61393215 in healthy volunteers.

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Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs.

Key publication

Repeated intravenous esketamine treatment in patients with ECT-resistant major depressive disorder

30 December 2022

Journal of Affective Disorders Reports Volume 10, December 2022, 100400

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