Key publication
156
Psychiatry
Methods & challenges

Key publication

Sodium Oxybate as a Potential New Treatment for Catatonia in Patients With Depression, Bipolar Disorder, or a Psychotic Disorder: Protocol for a Randomized Controlled Trial.

Key publication

A smartphone- and wearable-based biomarker for the estimation of unipolar depression severity.

Key publication

Item response theory in early phase clinical trials: Utilization of a reference model to analyze the Montgomery-Ã…sberg Depression Rating Scale.

Key publication

Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder.

Key publication

Fit for purpose of on-the-road driving and simulated driving: A randomised crossover study using the effect of sleep deprivation.

Key publication

Cognitive performance in healthy clinical trial participants and patients with the NeuroCart, a neurodegenerative disease measured with an automated neuropsychological and neurophysiological test battery.

Key publication

Decreased integrity of the monoaminergic tract is associated with a positive response to MPH in patients with vascular cognitive impairment - proof of principle study STREAM-VCI.

Key publication

Pharmacological characterization of the selective orexin-1 receptor antagonist JNJ-61393215 in healthy volunteers.

Key publication

Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs.