Key publication
906
Therapeutic Areas
Methods & challenges

Key publication

Sequential designs for clinical trials in amyotrophic lateral sclerosis.

1 December 2004

Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases

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Key publication

CGP 3466B has no effect on disease course of (G93A) mSOD1 transgenic mice.

1 December 2004

Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases

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Key publication

Subjective sleep disturbance in patients with partial epilepsy: a questionnaire-based study on prevalence and impact on quality of life.

Key publication

A validated HPLC assay to monitor riluzole plasma or serum concentrations in patients with amyotrophic lateral sclerosis.

Key publication

Pharmacokinetics of oral fumarates in healthy subjects.

Key publication

Ovariectomy and 17beta-estradiol modulate disease progression of a mouse model of ALS.

Key publication

Pharmacokinetics of rectal tramadol in postoperative paediatric patients.

Key publication

Glucose homeostasis in abdominal obesity: hepatic hyperresponsiveness to growth hormone action.

1 July 2004

American journal of physiology. Endocrinology and metabolism

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Key publication

Pharmacokinetic/pharmacodynamic assessment of tolerance to central nervous system effects of a 3 mg sustained release tablet of rilmenidine in hypertensive patients.