Key publication
906
Therapeutic Areas
Methods & challenges

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How it works.

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Eculizumab.

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Trabectedin.

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Randomized sequential trial of valproic acid in amyotrophic lateral sclerosis.

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The pharmacokinetic and pharmacodynamic effects of SL65.1498, a GABA-A alpha2,3 selective agonist, in comparison with lorazepam in healthy volunteers.

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Pharmacodynamic and pharmacokinetic effects of the intravenously administered CB1 receptor agonist Org 28611 in healthy male volunteers.

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Cannabis coadministration potentiates the effects of "ecstasy" on heart rate and temperature in humans.

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Efficacy of 3,4-diaminopyridine and pyridostigmine in the treatment of Lambert-Eaton myasthenic syndrome: a randomized, double-blind, placebo-controlled, crossover study.

Key publication

Validating a human model for anxiety using startle potentiated by cue and context: the effects of alprazolam, pregabalin, and diphenhydramine.