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The CHDR library contains a wealth of research and innovative publications that pushes our quality of work towards the highest standards.
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  • Pharmacological characterization of the selective orexin-1 receptor antagonist JNJ-61393215 in healthy volunteers.

    Brooks S, Zuiker R, Bleys C, Ziagkos D, Moyer JA, van Nueten L, Bonaventure P, Drevets WC, van Gerven J, Salvadore G, Jacobs GE

    Journal of psychopharmacology (Oxford, England), 2023 May

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  • First-in-patient study of OTL78 for intraoperative fluorescence imaging of prostate-specific membrane antigen-positive prostate cancer: a single-arm, phase 2a, feasibility trial.

    Stibbe JA, de Barros HA, Linders DGJ, Bhairosingh SS, Bekers EM, van Leeuwen PJ, Low PS, Kularatne SA, Vahrmeijer AL, Burggraaf J, van der Poel HG

    The Lancet. Oncology, 2023 May; 24(5):457-467

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  • A Biomarker Study in Patients with GBA1-Parkinson's Disease and Healthy Controls.

    den Heijer JM, Cullen VC, Pereira DR, Yavuz Y, de Kam ML, Grievink HW, Moerland M, Leymarie N, Khatri K, Sollomoni I, Spitalny L, Dungeon L, Hilt DC, Justman C, Lansbury P, Groeneveld GJ

    Movement disorders : official journal of the Movement Disorder Society, 2023 May; 38(5):783-795

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  • A multimodal, comprehensive characterization of a cutaneous wound model in healthy volunteers.

    Ten Voorde W, Saghari M, Boltjes J, de Kam ML, Zhuparris A, Feiss G, Buters TP, Prens EP, Damman J, Niemeyer-van der Kolk T, Moerland M, Burggraaf J, van Doorn MBA, Rissmann R

    Experimental dermatology, 2023 Apr

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  • Dermatoscopy and Optical Coherence Tomography in Vulvar High-Grade Squamous Intraepithelial Lesions and Lichen Sclerosus: A Prospective Observational Trial.

    Huisman BW, Pagan L, Naafs RGC, Ten Voorde W, Rissmann R, Piek JMJ, Damman J, Juachon MJ, Osse M, Niemeyer-van der Kolk T, van Hees CLM, van Poelgeest MIE

    Journal of lower genital tract disease, 2023 Mar

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  • Smartphone and Wearable Sensors for the Estimation of Facioscapulohumeral Muscular Dystrophy Disease Severity: Cross-sectional Study.

    Zhuparris A, Maleki G, Koopmans I, Doll RJ, Voet N, Kraaij W, Cohen A, van Brummelen E, De Maeyer JH, Groeneveld GJ

    JMIR formative research, 2023 Mar

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  • Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs.

    Ferreira GS, Dijkstra FM, Veening-Griffioen DH, Boon WPC, Schellekens H, Moors EHM, van Meer PJK, Stuurman FE, van Gerven JMA

    Translational psychiatry, 2023 Mar; 13(1):74

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  • Analysis and visualization of the course and burden over time of adverse drug reactions (ADRs) attributed to TNFα-inhibitors in patients with inflammatory rheumatic diseases (IRDs).

    de Boer M, Gosselt HR, Jansen J, van Doorn MBA, Hoentjen F, Nurmohamed MT, Spuls PI, Tas SW, Vonkeman HE, Jessurun NT

    Expert opinion on drug safety, 2023 Mar; 22(3):195-202

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  • LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease

    D. Jennings, S. Huntwork-Rodriguez, M.F.J.M. Vissers, V.M. Daryani, D. Diaz, M.S. Goo, J.J. Chen, R. Maciuca, K. Fraser, O.A. Mabrouk, J. van de Wetering de Rooij, J.A.A.C. Heuberger, G.J. Groeneveld, M. T Borin, A. Cruz-Herranz, D. Graham, K. Scearce-Levie, J. De Vicente, A. G. Henry, P. Chin, C. Ho, M.D. Troyer

    Official Journal of the International Parkinson and Movement Disorder Society, 2023 Feb

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Browse 1148 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Engineering and Analytics
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1148 publications in the CHDR library

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