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Pharmacological characterization of the selective orexin-1 receptor antagonist JNJ-61393215 in healthy volunteers.

Brooks S, Zuiker R, Bleys C, Ziagkos D, Moyer JA, van Nueten L, Bonaventure P, Drevets WC, van Gerven J, Salvadore G, Jacobs GE

Journal of psychopharmacology (Oxford, England), 2023 May

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First-in-patient study of OTL78 for intraoperative fluorescence imaging of prostate-specific membrane antigen-positive prostate cancer: a single-arm, phase 2a, feasibility trial.

Stibbe JA, de Barros HA, Linders DGJ, Bhairosingh SS, Bekers EM, van Leeuwen PJ, Low PS, Kularatne SA, Vahrmeijer AL, Burggraaf J, van der Poel HG

The Lancet. Oncology, 2023 May; 24(5):457-467

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A Biomarker Study in Patients with GBA1-Parkinson's Disease and Healthy Controls.

den Heijer JM, Cullen VC, Pereira DR, Yavuz Y, de Kam ML, Grievink HW, Moerland M, Leymarie N, Khatri K, Sollomoni I, Spitalny L, Dungeon L, Hilt DC, Justman C, Lansbury P, Groeneveld GJ

Movement disorders : official journal of the Movement Disorder Society, 2023 May; 38(5):783-795

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A multimodal, comprehensive characterization of a cutaneous wound model in healthy volunteers.

Ten Voorde W, Saghari M, Boltjes J, de Kam ML, Zhuparris A, Feiss G, Buters TP, Prens EP, Damman J, Niemeyer-van der Kolk T, Moerland M, Burggraaf J, van Doorn MBA, Rissmann R

Experimental dermatology, 2023 Apr

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Dermatoscopy and Optical Coherence Tomography in Vulvar High-Grade Squamous Intraepithelial Lesions and Lichen Sclerosus: A Prospective Observational Trial.

Huisman BW, Pagan L, Naafs RGC, Ten Voorde W, Rissmann R, Piek JMJ, Damman J, Juachon MJ, Osse M, Niemeyer-van der Kolk T, van Hees CLM, van Poelgeest MIE

Journal of lower genital tract disease, 2023 Mar

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Smartphone and Wearable Sensors for the Estimation of Facioscapulohumeral Muscular Dystrophy Disease Severity: Cross-sectional Study.

Zhuparris A, Maleki G, Koopmans I, Doll RJ, Voet N, Kraaij W, Cohen A, van Brummelen E, De Maeyer JH, Groeneveld GJ

JMIR formative research, 2023 Mar

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Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs.

Ferreira GS, Dijkstra FM, Veening-Griffioen DH, Boon WPC, Schellekens H, Moors EHM, van Meer PJK, Stuurman FE, van Gerven JMA

Translational psychiatry, 2023 Mar; 13(1):74

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Analysis and visualization of the course and burden over time of adverse drug reactions (ADRs) attributed to TNFα-inhibitors in patients with inflammatory rheumatic diseases (IRDs).

de Boer M, Gosselt HR, Jansen J, van Doorn MBA, Hoentjen F, Nurmohamed MT, Spuls PI, Tas SW, Vonkeman HE, Jessurun NT

Expert opinion on drug safety, 2023 Mar; 22(3):195-202

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LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease

D. Jennings, S. Huntwork-Rodriguez, M.F.J.M. Vissers, V.M. Daryani, D. Diaz, M.S. Goo, J.J. Chen, R. Maciuca, K. Fraser, O.A. Mabrouk, J. van de Wetering de Rooij, J.A.A.C. Heuberger, G.J. Groeneveld, M. T Borin, A. Cruz-Herranz, D. Graham, K. Scearce-Levie, J. De Vicente, A. G. Henry, P. Chin, C. Ho, M.D. Troyer

Official Journal of the International Parkinson and Movement Disorder Society, 2023 Feb

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