Key publication
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Therapeutic Areas
Methods & challenges

Key publication

DNL104, a centrally penetrant RIPK1 inhibitor, inhibits RIP1 kinase phosphorylation in a randomized phase I ascending dose study in healthy volunteers.

Key publication

Whole blood assay as a model for in vitro evaluation of inflammasome activation and subsequent caspase-mediated interleukin-1 beta release.

Key publication

No effect of topical digoxin and furosemide gel for patients with external anogenital warts.

20 August 2019

Journal of the European Academy of Dermatology and Venereology : JEADV

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Key publication

Mobile e-diary application facilitates the monitoring of patient-reported outcomes and a high treatment adherence for clinical trials in dermatology.

16 August 2019

Journal of the European Academy of Dermatology and Venereology : JEADV

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Key publication

The Pharmacodynamic Effects of a Dopamine-Somatostatin Chimera Agonist on the Cardiovascular System.

Key publication

Evaluation of the Novel PET Tracer [C]HACH242 for Imaging the GluN2B NMDA Receptor in Non-Human Primates.

Key publication

Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABA partial agonist, in humans.

Key publication

A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery.

Key publication

Parasitic pharmacology: A plausible mechanism of action for cannabidiol.