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Prevalent levels of RSV serum neutralizing antibodies in healthy adults outside the RSV-season.

van der Plas JL, Verdijk P, van Brummelen EMJ, Jeeninga RE, Roestenberg M, Burggraaf J, Kamerling IMC

Human vaccines & immunotherapeutics, 2019 Nov

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Immunomonitoring of Tacrolimus in Healthy Volunteers: The First Step from PK- to PD-Based Therapeutic Drug Monitoring?

In 't Veld AE, Grievink HW, Saghari M, Stuurman FE, de Kam ML, de Vries APJ, de Winter BCM, Burggraaf J, Cohen AF, Moerland M

International journal of molecular sciences, 2019 Sep

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DNL104, a centrally penetrant RIPK1 inhibitor, inhibits RIP1 kinase phosphorylation in a randomized phase I ascending dose study in healthy volunteers.

Grievink HW, Heuberger JAAC, Huang F, Chaudhary R, Birkhoff WAJ, Tonn GR, Mosesova S, Erickson R, Moerland M, Haddick PCG, Scearce-Levie K, Ho C, Groeneveld GJ

Clinical pharmacology and therapeutics, 2019 Aug

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Whole blood assay as a model for in vitro evaluation of inflammasome activation and subsequent caspase-mediated interleukin-1 beta release.

Tran TAT, Grievink HW, Lipinska K, Kluft C, Burggraaf J, Moerland M, Tasev D, Malone KE

PloS one, 2019 Aug; 14(4):e0214999

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Spotlight Commentary: How to prove pharmacology of immunomodulatory drugs in a phase 1 trial?

Rissmann R, Szabadi E

British journal of clinical pharmacology, 2019 Jun; 85(7):1389-1390

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The effect of repeated methotrexate injections on the quality of life of children with rheumatic diseases.

Jacobse J, Ten Voorde W, Rissmann R, Burggraaf J, Ten Cate R, Schrier L

European journal of pediatrics, 2019 Jan; 178(1):17-20

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The ultraviolet B inflammation model: postinflammatory hyperpigmentation and validation of a reduced UVB exposure paradigm for inducing hyperalgesia in healthy subjects.

Siebenga PS, van Amerongen G, Klaassen ES, de Kam ML, Rissmann R, Groeneveld GJ

European journal of pain (London, England), 2018 Dec

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Effects of two antihistamine drugs on actual driving performance.

Cohen AF, Posner J

British medical journal (Clinical research ed.), 2018 Dec; 288(6421):935

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Evidence of NI-0101 pharmacological activity, an anti-TLR4 antibody, in a randomized phase I dose escalation study in healthy volunteers receiving LPS.

Monnet E, Lapeyre G, Poelgeest EV, Jacqmin P, Graaf K, Reijers J, Moerland M, Burggraaf J, Min C

Clinical pharmacology and therapeutics, 2018 Dec; 101(2):200-208

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