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Pharmacological vs. classical approaches in the design of first in man clinical drug trials.

1 December 2017. doid: 10.1111/bcp.13422

van den Bogert CA, Cohen AF, Leufkens HGM, van Gerven JMA

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The aims of the present study were to investigate the role of pharmacology in the design of first-in-man (FIM) trials in the Netherlands, and to evaluate the change in design approaches between 2007 and 2015.

Advancing the boundaries of clinical drug development

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