How it works

Today's clinicians can turn to a number of resources to learn more about the drugs they prescribe. They are encouraged to use treatment guidelines or formularies to select drug therapy. If no algorithm exists, they are expected to use evidence-based medical practices to determine the most appropriate treatment. A search of the available literature about a new drug entity will result in numerous articles about the drug's effectiveness and its place of therapy, the likelihood of adverse effects compared to standard of care, or perhaps the pharmacokinetic profiles in genetically diverse populations. Even the Journal is heavily populated with pharmacoepidemiological data. So where is information that will satisfy our need to understand pharmacological mechanisms of drug action?