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  • Pronounced effects of the combination of a new thromboxane antagonist (GR32191) and heparin on bleeding time in man.

    de Boer A, Kroon JM, Kroon C, van Vliet A, Schoemaker HC, Breimer DD, Donoghue S, Cohen AF

    Thrombosis and haemostasis, 1992 Jul; 68(1):24-9

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  • Long-term effects of tolrestat on symptomatic diabetic sensory polyneuropathy.

    van Gerven JM, Lemkes HH, van Dijk JG

    Journal of diabetes and its complications, 1992 Apr; 6(1):45-8

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  • Intraindividual variability in nifedipine pharmacokinetics and effects in healthy subjects.

    Soons PA, Schoemaker HC, Cohen AF, Breimer DD

    Journal of clinical pharmacology, 1992 Mar; 32(4):324-31

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  • Cardiovascular effects of a novel enkephalin analogue, 443C81, in humans.

    Cohen AF, Harkin N, Posner J

    Journal of cardiovascular pharmacology, 1990 Sep; 16(3):455-60

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  • Single- and multiple-dose nisoldipine kinetics and effects in the young, the middle-aged, and the elderly.

    van Harten J, Burggraaf J, Ligthart GJ, van Brummelen P, Breimer DD

    Clinical pharmacology and therapeutics, 1989 May; 45(6):600-7

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  • The contribution of nisoldipine-induced changes in liver blood flow to its pharmacokinetics after oral administration.

    van Harten J, Burggraaf J, Danhof M, van Brummelen P, Breimer DD

    British journal of clinical pharmacology, 1989 Apr; 27(5):581-6

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  • Influence of renal function on the pharmacokinetics and cardiovascular effects of nisoldipine after single and multiple dosing.

    van Harten J, Burggraaf J, van Brummelen P, Breimer DD

    Clinical pharmacokinetics, 1989 Jan; 16(1):55-64

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    Cardiovascular & Metabolic disease

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    • Coagulation

    Internal Medicine

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  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1016 publications in the CHDR library

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