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Pharmacology in translation: the preclinical and early clinical profile of the novel α2/3 functionally selective GABA receptor positive allosteric modulator PF-06372865.

Nickolls SA, Gurrell R, van Amerongen G, Kammonen J, Cao L, Brown AR, Stead C, Mead A, Watson C, Hsu C, Owen RM, Pike A, Fish RL, Chen L, Qiu R, Morris ED, Feng G, Whitlock M, Gorman D, van Gerven J, Reynolds DS, Dua P, Butt RP

British journal of pharmacology, 2018 Feb; 175(4):708-725

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The effects of intranasal esketamine (84 mg) and oral mirtazapine (30 mg) on on-road driving performance: a double-blind, placebo-controlled study.

van de Loo AJAE, Bervoets AC, Mooren L, Bouwmeester NH, Garssen J, Zuiker R, van Amerongen G, van Gerven J, Singh J, der Ark PV, Fedgchin M, Morrison R, Wajs E, Verster JC

Psychopharmacology, 2017 Nov; 234(21):3175-3183

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Question-based Drug Development for psilocybin.

Dijkstra FM, Jacobs GE, Cohen AF

The lancet. Psychiatry, 2016 Aug; 3(9):806-7

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Reliability of System Identification Techniques to Assess Standing Balance in Healthy Elderly.

Pasma JH, Engelhart D, Maier AB, Aarts RG, van Gerven JM, Arendzen JH, Schouten AC, Meskers CG, van der Kooij H

PloS one, 2016 Apr; 11(3):e0151012

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Single-dose serotonergic stimulation shows widespread effects on functional brain connectivity.

Klaassens BL, van Gorsel HC, Khalili-Mahani N, van der Grond J, Wyman BT, Whitcher B, Rombouts SA, van Gerven JM

NeuroImage, 2015 Nov

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Lessons Learned and Potentials for Improvement in CNS Drug Development: ISCTM Section on Designing the Right Series of Experiments.

Szabo ST, Kinon BJ, Brannan SK, Krystal AK, van Gerven JM, Mahableshwarkar A, Sachs GS

Innovations in clinical neuroscience, 2015 Apr; 12(3-4):11S-25S

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Optimizing the glutamatergic challenge model for psychosis, using S+ -ketamine to induce psychomimetic symptoms in healthy volunteers.

Kleinloog D, Uit den Boogaard A, Dahan A, Mooren R, Klaassen E, Stevens J, Freijer J, van Gerven J

Journal of psychopharmacology (Oxford, England), 2015 Mar; 29(4):401-13

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The effects of the nonselective benzodiazepine lorazepam and the α2 /α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels.

Te Beek ET, Chen X, Jacobs GE, Nahon KJ, de Kam ML, Lappalainen J, Cross AJ, van Gerven JM, Hay JL

Clinical pharmacology in drug development, 2015 Feb; 4(2):149-54

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Ketamine interactions with biomarkers of stress: a randomized placebo-controlled repeated measures resting-state fMRI and PCASL pilot study in healthy men.

Khalili-Mahani N, Niesters M, van Osch MJ, Oitzl M, Veer I, de Rooij M, van Gerven J, van Buchem MA, Beckmann CF, Rombouts SA, Dahan A

NeuroImage, 2015 Feb

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