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Browse our Immunophenotyping Inflammatory challenges publications

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  • Impact of oral administration of single strain spp. on immune responses to keyhole limpet hemocyanin immunization and gut microbiota: A randomized placebo-controlled trial in healthy volunteers.

    Saghari M, Gal P, Grievink HW, Klaassen ES, Itano A, McHale D, Moerland M

    Frontiers in immunology, 2023 May

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  • Analysis and visualization of the course and burden over time of adverse drug reactions (ADRs) attributed to TNFα-inhibitors in patients with inflammatory rheumatic diseases (IRDs).

    de Boer M, Gosselt HR, Jansen J, van Doorn MBA, Hoentjen F, Nurmohamed MT, Spuls PI, Tas SW, Vonkeman HE, Jessurun NT

    Expert opinion on drug safety, 2023 Mar; 22(3):195-202

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  • A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis.

    Liu F, Aulin LBS, Kossen SSA, Cathalina J, Bremmer M, Foks AC, van der Graaf PH, Moerland M, van Hasselt JGC

    Journal of pharmacokinetics and pharmacodynamics, 2022 Oct

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  • Monitoring of Ex vivo Cyclosporin A Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics

    Aliede E. in ’t Veld, Manon A. A. Jansen, Bertine W. Huisman, Mascha Schoonakker, Marieke L. de Kam, Dirk Jan A. R. Moes, Mariëtte I. E. van Poelgeest, Jacobus Burggraaf and Matthijss Moerland

    Pharmaceutics, 2022 Sep

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  • Characterization of KLH-driven immune responses in clinical studies: A systematic review

    Mahdi Saghari, Manon A. A. Jansen, Hendrika W. Grievink, Robert Rissmann, Matthijs Moerland

    Front. Drug. Discov, 2022 Sep

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  • Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?

    Damman J, Mooyaart AL, Bosch TPPVD, Seelen MA, Doorn MBV

    Molecular immunology, 2022 Mar

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  • Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers.

    Buters TP, Hameeteman PW, Jansen IME, van Hindevoort FC, Ten Voorde W, Florencia E, Osse M, de Kam ML, Grievink HW, Schoonakker M, Patel AA, Yona S, Gilroy DW, Lubberts E, Damman J, Feiss G, Rissmann R, Jansen MAA, Burggraaf J, Moerland M

    British journal of clinical pharmacology, 2021 Jul

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  • A randomized controlled trial with a delayed-type hypersensitivity model using keyhole limpet haemocyanin to evaluate adaptive immune responses in man.

    Saghari M, Gal P, Ziagkos D, Burggraaf J, Powell JF, Brennan N, Rissmann R, van Doorn MBA, Moerland M

    British journal of clinical pharmacology, 2020 Oct

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  • Omiganan Enhances Imiquimod-Induced Inflammatory Responses in Skin of Healthy Volunteers.

    Niemeyer-van der Kolk T, Assil S, Buters TP, Rijsbergen M, Klaassen ES, Feiss G, Florencia E, Prens EP, Burggraaf J, van Doorn MBA, Rissmann R, Moerland M

    Clinical and translational science, 2020 Mar

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Browse 1079 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Engineering and Analytics
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1079 publications in the CHDR library

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