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  • A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis.

    Liu F, Aulin LBS, Kossen SSA, Cathalina J, Bremmer M, Foks AC, van der Graaf PH, Moerland M, van Hasselt JGC

    Journal of pharmacokinetics and pharmacodynamics, 2022 Oct

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  • Monitoring of Ex vivo Cyclosporin A Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics

    Aliede E. in ’t Veld, Manon A. A. Jansen, Bertine W. Huisman, Mascha Schoonakker, Marieke L. de Kam, Dirk Jan A. R. Moes, Mariëtte I. E. van Poelgeest, Jacobus Burggraaf and Matthijss Moerland

    Pharmaceutics, 2022 Sep

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  • Characterization of KLH-driven immune responses in clinical studies: A systematic review

    Mahdi Saghari, Manon A. A. Jansen, Hendrika W. Grievink, Robert Rissmann, Matthijs Moerland

    Front. Drug. Discov, 2022 Sep

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  • A randomized controlled trial with a delayed-type hypersensitivity model using keyhole limpet haemocyanin to evaluate adaptive immune responses in man.

    Saghari M, Gal P, Ziagkos D, Burggraaf J, Powell JF, Brennan N, Rissmann R, van Doorn MBA, Moerland M

    British journal of clinical pharmacology, 2020 Oct

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  • Impact of (chemo)radiotherapy on immune cell composition and function in cervical cancer patients.

    van Meir H, Nout RA, Welters MJ, Loof NM, de Kam ML, van Ham JJ, Samuels S, Kenter GG, Cohen AF, Melief CJ, Burggraaf J, van Poelgeest MI, van der Burg SH

    Oncoimmunology, 2017 Aug; 6(2):e1267095

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  • Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses.

    Welters MJ, van der Sluis TC, van Meir H, Loof NM, van Ham VJ, van Duikeren S, Santegoets SJ, Arens R, de Kam ML, Cohen AF, van Poelgeest MI, Kenter GG, Kroep JR, Burggraaf J, Melief CJ, van der Burg SH

    Science translational medicine, 2016 Apr; 8(334):334ra52

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  • The need for improvement of the treatment of advanced and metastatic cervical cancer, the rationale for combined chemo-immunotherapy.

    van Meir H, Kenter GG, Burggraaf J, Kroep JR, Welters MJ, Melief CJ, van der Burg SH, van Poelgeest MI

    Anti-cancer agents in medicinal chemistry, 2014 Jan; 14(2):190-203

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Browse 1016 publications in the CHDR library

  • Clinical studies & Development
  • CHDR's story
  • People
  • Education
  • Library

Clinical development & Services

  • Therapeutic areas

    Central Nervous System

    • Neurology
    • Pain
    • Psychiatry
    • Sleep disorders

    Immunology & Inflammation

    • Immuno-inflammation
    • Dermatology
    • Immuno-Oncology

    Cardiovascular & Metabolic disease

    • Endocrinology
    • Macro- and microvasculature
    • Coagulation

    Internal Medicine

    • Infectious diseases
    • Biologicals
    • Pulmonology
  • Methods & Biomarkers

    Central Nervous System

    • NeuroCart®
    • PainCart®
    • Pharmacological Challenge Models
    • CSF sampling
    • Driving Performance
    • Ethanol interaction
    • CO2 inhalation challenge
    • Transcranial Magnetic Stimulation (TMS)

    Translational Biomarkers

    • Isolation of primary human cells
    • Immunophenotyping
    • Cell cultures and incubations/challenges

    Immunology & Inflammation

    • Dermatological assessments
    • Inflammatory challenges
    • LPS Challenge

    Cardiovascular & Metabolic disease

    • Metabolic and endocrine responses
    • Cardiac and endovascular function assessments

    Imaging Techniques

    • fMRI
    • PET Imaging
    • Image-guided surgery
  • Trial Services
    • Recruitment
    • Pharmacy
    • Regulatory affairs
    • Biomarker Laboratory
    • Cardiology Services
    • Pharmacokinetics and pharmacometrics
    • Data Management
    • Trial@home
    Participate in a Clinical Trial proefpersoon.nl

Browse 1016 publications in the CHDR library

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